the goodman group
university of cambridge  


   Goodman Group: Department Publications

Formation of Cucurbit[8]uril-Based Supramolecular Hydrogel Beads Using Droplet-Based Microfluidics

Xuejiao Xu, Eric A Appel, Xin Liu, Richard M Parker, Oren A Scherman, and Chris Abell
Biomacromolecules DOI: 10.1021/acs.biomac.5b01048


Synthesis, characterization and in vitro evaluation of novel enantiomerically-pure sulphonamide antimalarials

Anusha Sebastian, Ameya Sinha, Pokunoth C Baburajeev, Trang TT Chu, Jessin Mathai, Kanchugarakoppal S Rangappa, Salundi Basappa, Rajesh C Das, julian e fuchs, Andreas Bender, Huang Ximei, Peter Rainer Preiser, Shivananju NanjundaSwamy
Organic and Biomolecular Chemistry DOI: 10.1039/C5OB01479D


Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α-Synuclein Oligomers

Mathew H Horrocks, Laura Tosatto, Alexander J Dear, Gonzalo A Garcia, Marija Iljina, Nunilo Cremades, Mauro Dalla Serra, Tuomas P J Knowles, Christopher M Dobson, and David Klenerman
Analytical Chemistry DOI: 10.1021/acs.analchem.5b01811


Mechanistic Insights into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C–H Activation

Adam P Smalley and Matthew J Gaunt
Journal of the American Chemical Society DOI: 10.1021/jacs.5b05529


Mapping Structural Changes in Electrode Materials: Application of the Hybrid Eigenvector-Following Density Functional Theory (DFT) Method to Layered Li0.5MnO2

Ieuan D Seymour, Sudip Chakraborty, Derek S Middlemiss, David J Wales, and Clare P Grey
Chemistry of Materials DOI: 10.1021/acs.chemmater.5b01674


Peptide Anchor for Folate-Targeted Liposomal Delivery

Eugénia Nogueira, Irene C Mangialavori, Ana Loureiro, Nuno G Azoia, Marisa P Sárria, Patrícia Nogueira, Jaime Freitas, Johan Härmark, Ulyana Shimanovich, Alexandra Rollett, Ghislaine Lacroix, Gonçalo J L Bernardes, Georg Guebitz, Hans Hebert, Alexandra Moreira, Alexandre M Carmo, Juan Pablo F C Rossi, Andreia C Gomes, Ana Preto, and Artur Cavaco-Paulo
Biomacromolecules DOI: 10.1021/acs.biomac.5b00823


Post-assembly Modification of Tetrazine-Edged FeII4L6 Tetrahedra

Derrick A Roberts, Ben S Pilgrim, Jonathan D Cooper, Tanya K Ronson, Salvatore Zarra, and Jonathan R Nitschke
Journal of the American Chemical Society DOI: 10.1021/jacs.5b05080


Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates

Maya A Wright, Francesco A Aprile, Paolo Arosio, Michele Vendruscolo, Christopher M Dobson, Tuomas Knowles
Chemical Communications DOI: 10.1039/C5CC03689E


Chromatin Unfolding by Epigenetic Modifications Explained by Dramatic Impairment of Internucleosome Interactions: A Multiscale Computational Study

Rosana Collepardo-Guevara, Guillem Portella, Michele Vendruscolo, Daan Frenkel, Tamar Schlick, and Modesto Orozco
Journal of the American Chemical Society DOI: 10.1021/jacs.5b04086


A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate

Francesco A Aprile, Pietro Sormanni, and Michele Vendruscolo
Biochemistry DOI: 10.1021/acs.biochem.5b00459


Divergence from the classical hydroboration reactivity; boron containing materials through a hydroboration cascade of small cyclic dienes.

Anna Andreou, Michal Leskes, Pablo Jambrina, Gary Tustin, Clare P Grey, Edina Rosta, Prof Oren Scherman
Chemical Science DOI: 10.1039/C4SC02729A


Molecular Rotors Provide Insights into Microscopic Structural Changes During Protein Aggregation

Alexander J Thompson, Therese W Herling, Markéta Kubánková, Aurimas Vyšniauskas, Tuomas P J Knowles, and Marina K Kuimova
Journal of Physical Chemistry B DOI: 10.1021/acs.jpcb.5b05099


Finite pulse effects in CPMG pulse trains on paramagnetic materials

Michal Leskes, Clare P Grey
PCCP DOI: 10.1039/C5CP02331A


Guaianolides and a seco-Eudesmane from the Resinous Exudates of Cushion Bush (Leucophyta brownii) and Evaluation of Their Cytostatic and Anti-inflammatory Activity

Mette G Hyldgaard, Stig Purup, Andrew D Bond, Xavier C Fretté, Haiyan Qu, Katrine T Jensen, and Lars P Christensen
Journal of Natural Products DOI: 10.1021/acs.jnatprod.5b00208


Catalytic polymeric nanocomposites via cucurbit[n]uril host-guest interactions

Yuchao Wu, Yang Lan, Ji Liu, Oren A Scherman
Nanoscale DOI: 10.1039/C5NR03647J


Differentially Addressable Cavities within Metal–Organic Cage-Cross-Linked Polymeric Hydrogels

Jonathan A Foster, Richard M Parker, Ana M Belenguer, Norifumi Kishi, Sam Sutton, Chris Abell, and Jonathan R Nitschke
Journal of the American Chemical Society DOI: 10.1021/jacs.5b05507


Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy

Yulia Pustovalova, Predrag Kukic, Michele Vendruscolo, and Dmitry M Korzhnev
Biochemistry DOI: 10.1021/acs.biochem.5b00345


Assembly of soft anisotropic particles into a Kagome lattice

Szilard N Fejer, David J Wales
Soft Matter DOI: 10.1039/C5SM01191D


Energy landscapes of a hairpin peptide including NMR chemical shift restraints

Joanne M Carr, Chris S Whittleston, David C Wade, David J Wales
PCCP DOI: 10.1039/C5CP01259G


Preparation and Supramolecular Recognition of Multivalent Peptide–Polysaccharide Conjugates by Cucurbit[8]uril in Hydrogel Formation

Matthew J Rowland, Marina Atgie, Dominique Hoogland, and Oren A Scherman
Biomacromolecules DOI: 10.1021/acs.biomac.5b00680





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department of chemistry University of Cambridge