the goodman group this list is a product of research in the Goodman Group;
it is not the official department of chemistry list of
academics or academic publications
university of cambridge  


List papers in: all subjects | Biological | Materials | Physical | Synthesis | Theory, Modelling and Informatics
Christopher M Dobson FRS Publications (2008)


Self-Templated Nucleation In Peptide And Protein Aggregation.
Auer S, Dobson CM, Vendruscolo M, Maritan A
Physical Review Letters 2008, 101, 258101-


A Generic Mechanism Of Emergence Of Amyloid Protofilaments From Disordered Oligomeric Aggregates.
Auer S, Meersman F, Dobson CM, Vendruscolo M
PLoS Computational Biology 2008, 4, e1000222- DOI: 10.1371/journal.pcbi.1000222


Recombinant Amyloid Beta-Peptide Production By Coexpression With An Affibody Ligand
Macao B, Hoyer W, Sandberg A, Brorsson AC, Dobson CM, Hard T
BMC Biotechnology 2008, 8, - DOI: 10.1186/1472-6750-8-82


Engineering A Camelid Antibody Fragment That Binds To The Active Site Of Human Lysozyme And Inhibits Its Conversion Into Amyloid Fibrils.
Chan PH, Pardon E, Menzer L, De Genst E, Kumita JR, Christodoulou J, Saerens D, Brans A, Bouillenne F, Archer DB, Robinson CV, Muyldermans S, Matagne A, Redfield C, Wyns L, Dobson CM, Dumoulin M
Biochemistry 2008, 47, 11041-11054 DOI: 10.1021/bi8005797


Structure And Dynamics Of A Partially Folded Protein Are Decoupled From Its Mechanism Of Aggregation.
Calloni G, Lendel C, Campioni S, Giannini S, Gliozzi A, Relini A, Vendruscolo M, Dobson CM, Salvatella X, Chiti F
Journal of the American Chemical Society 2008, 130, 13040-13050 DOI: 10.1021/ja8029224


Immunological Features Of Alpha-Synuclein In Parkinson'S Disease.
Roodveldt C, Christodoulou J, Dobson CM
Journal of Cell and Molecular Medicine 2008, 12, 1820-1829 DOI: 10.1111/j.1582-4934.2008.00450.x


Label-Free Detection Of Amyloid Growth With Microcantilever Sensors
Knowles TPJ, Shu W, Huber F, Lang HP, Gerber C, Dobson CM, Welland ME
Nanotechnology 2008, 19, - DOI: 10.1088/0957-4484/19/38/384007


Direct Characterization Of Amyloidogenic Oligomers By Single-Molecule Fluorescence.
Orte A, Birkett NR, Clarke RW, Devlin GL, Dobson CM, Klenerman D
Proceedings of the National Academy of Sciences of USA 2008, 105, 14424-14429 DOI: 10.1073/pnas.0803086105


Biot 336-Exploring The Energy Landscape Of Human Lysozyme Toward An Elucidation Of The Molecular Mechanism Of Systemic Amyloidosis
Dhulesia A, Kumita JR, Nietlispach D, Salvatella X, Dobson CM
ACS National Meeting Book of Abstracts 2008, 236, -


Phys 90-Life On The Edge: The Origins And Proliferation Of Protein Misfolding Diseases
Dobson CM
ACS National Meeting Book of Abstracts 2008, 236, -


Biot 243-Biophysical Study Of The Aggregation Of Human Lysozyme Into Amyloid Fibrils
Dhulesia A, Baldwin AJ, Mossuto MF, Salvatella X, Dobson CM
ACS National Meeting Book of Abstracts 2008, 236, -


Characterizing The First Steps Of Amyloid Formation For The Ccbeta Peptide.
Strodel B, Fitzpatrick AW, Vendruscolo M, Dobson CM, Wales DJ
The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical 2008, 112, 9998-10004 DOI: 10.1021/jp801222x


Life On The Edge: The Nature And Origins Of Protein Misfolding Diseases
Dobson CM
Journal of Peptide Science 2008, 14, 26-26


Prediction Of Aggregation-Prone Regions In Structured Proteins.
Tartaglia GG, Pawar AP, Campioni S, Dobson CM, Chiti F, Vendruscolo M
Journal of Molecular Biology 2008, 380, 425-436 DOI: 10.1016/j.jmb.2008.05.013


Life On The Edge: The Origins And Proliferation Of Protein Misfolding Diseases
Dobson CM
The Federation of European Biochemical Societies (FEBS) Journal 2008, 275, 27-27


Molecular Determinants Of The Aggregation Behavior Of Alpha- And Beta-Synuclein.
Rivers RC, Kumita JR, Tartaglia GG, Dedmon MM, Pawar A, Vendruscolo M, Dobson CM, Christodoulou J
Protein Science 2008, 17, 887-898 DOI: 10.1110/ps.073181508


A Coupled Equilibrium Shift Mechanism In Calmodulin-Mediated Signal Transduction.
Gsponer J, Christodoulou J, Cavalli A, Bui JM, Richter B, Dobson CM, Vendruscolo M
Structure 2008, 16, 736-746 DOI: 10.1016/j.str.2008.02.017


Functionalised Amyloid Fibrils For Roles In Cell Adhesion
Gras SL, Tickler AK, Squires AM, Devlin GL, Horton MA, Dobson CM, MacPhee CE
Biomaterials 2008, 29, 1553-1562 DOI: 10.1016/j.biomaterials.2007.11.028


Determination Of The Transition State Ensemble For The Folding Of Ubiquitin From A Combination Of Phi And Psi Analyses.
Várnai P, Dobson CM, Vendruscolo M
Journal of Molecular Biology 2008, 377, 575-588 DOI: 10.1016/j.jmb.2008.01.012


Conservation Of Mechanism, Variation Of Rate: Folding Kinetics Of Three Homologous Four-Helix Bundle Proteins
Dalal S, Canet D, Kaiser SE, Dobson CM, Regan L
Protein Engineering Design and Selection 2008, 21, 197-206 DOI: 10.1093/protein/gzm088


Characterization Of Folding The Four-Helix Bundle Protein Rop By Real-Time Nmr
van Nuland NAJ, Dobson CM, Regan L
Protein Engineering Design and Selection 2008, 21, 165-170 DOI: 10.1093/protein/gzm081


Protein Misfolding And Disease: From The Test Tube To The Organism.
Luheshi LM, Crowther DC, Dobson CM
Current Opinion in Chemical Biology 2008, 12, 25-31 DOI: 10.1016/j.cbpa.2008.02.011


Measurement Of Amyloid Fibril Length Distributions By Inclusion Of Rotational Motion In Solution Nmr Diffusion Measurements
Baldwin AJ, Anthony-Cahill SJ, Knowles TPJ, Lippens G, Christodoulou J, Barker PD, Dobson CM
Angewandte Chemie International Edition 2008, 47, 3385-3387 DOI: 10.1002/anie.200703915


“Protein Folding And Misfolding: From Atoms To Organisms" In Physical Biology: From Atoms To Medicine
Dobson CM
2008, , 289-335


Calculation Of The Free Energy Barriers In The Oligomerisation Of Abeta Peptide Fragments.
Cheon M, Favrin G, Chang I, Dobson CM, Vendruscolo M
Frontiers in Bioscience 2008, 13, 5614-5622



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