Synthesis Publications (2011)
- Stereocontrolled total synthesis of (+)-concanamycin F: the strategic use of boron-mediated aldol reactions of chiral ketones
- Paterson I, Doughty VASN, McLeod MD, Trieselmann T
- TETRAHEDRON 2011, 0, 10119-10128. DOI: 10.1016/j.tet.2011.09.012
- Decoding genomes at high speed: implications for science and medicine.
- Balasubramanian S
- Angew Chem Int Ed Engl 2011, 50, 12406-12410. DOI: 10.1002/anie.201106707
- A cocrystal strategy to tune the luminescent properties of stilbene-type organic solid-state materials.
- Yan D, Delori A, Lloyd GO, Friščić T, Day GM, Jones W, Lu J, Wei M, Evans DG, Duan X
- Angew Chem Int Ed Engl 2011, 2, 12483-12486. DOI: 10.1002/anie.201106391
- The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
- Roper KA, Lange H, Polyzos A, Berry MB, Baxendale IR, Ley SV
- BEILSTEIN J ORG CHEM 2011, 7, 1648-1655. DOI: 10.3762/bjoc.7.194
- Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site (vol 19, pg 1691, 2011)
- Bolanos-Garcia VM, Lischetti T, Matak-Vinkovic D, Cota E, Simpson PJ, Chirgadze DY, Spring DR, Robinson CV, Nilsson J, Blundell TL
- STRUCTURE 2011, 0, 1895-1895. DOI: 10.1016/j.str.2011.11.011
- Subcomponent Self-Assembly and Guest-Binding Properties of Face-Capped Fe(4)L(4)(8+) Capsules.
- Bilbeisi RA, Clegg JK, Elgrishi N, Hatten XD, Devillard M, Breiner B, Mal P, Nitschke JR
- J Am Chem Soc 2011, -. DOI: 10.1021/ja2092272
- 2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa.
- Ha DG, Merritt JH, Hampton TH, Hodgkinson JT, Janecek M, Spring DR, Welch M, O'Toole GA
- J Bacteriol 2011, 193, 6770-6780. DOI: 10.1128/JB.05929-11
- Aryl-aryl bond formation by the fluoride-free cross-coupling of aryldisiloxanes with aryl bromides.
- Boehner CM, Frye EC, O'Connell KM, Galloway WR, Sore HF, Dominguez PG, Norton D, Hulcoop DG, Owen M, Turner G, Crawford C, Horsley H, Spring DR
- Chemistry 2011, 17, 13230-13239. DOI: 10.1002/chem.201102285
- Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site.
- Bolanos-Garcia VM, Lischetti T, Matak-Vinković D, Cota E, Simpson PJ, Chirgadze DY, Spring DR, Robinson CV, Nilsson J, Blundell TL
- Structure 2011, 19, 1691-1700. DOI: 10.1016/j.str.2011.09.017
- Exploring isonitrile-based click chemistry for ligation with biomolecules.
- Stöckmann H, Neves AA, Stairs S, Brindle KM, Leeper FJ
- Org Biomol Chem 2011, 9, 7303-7305. DOI: 10.1039/C1OB06424J
- PNA to DNA to microarray decoding facilitates ligand discovery.
- Galloway WR, Spring DR
- Chem Biol 2011, 18, 1209-1210. DOI: 10.1016/j.chembiol.2011.10.002
- A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands
- Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao HB
- NAT CHEM 2011, 3, 782-787. DOI: 10.1038/NCHEM.1126
- Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery.
- Philpott M, Yang J, Tumber T, Fedorov O, Uttarkar S, Filippakopoulos P, Picaud S, Keates T, Felletar I, Ciulli A, Knapp S, Heightman TD
- Mol Biosyst 2011, 7, 2899-2908. DOI: 10.1039/C1MB05099K
- Transition metal complexes of the pentacyanocyclopentadienide anion.
- Less RJ, Wilson TC, McPartlin M, Wood PT, Wright DS
- Chem Commun (Camb) 2011, 47, 10007-10009. DOI: 10.1039/C1CC13021H
- Metastability of native proteins and the phenomenon of amyloid formation.
- Baldwin AJ, Knowles TP, Tartaglia GG, Fitzpatrick AW, Devlin GL, Shammas SL, Waudby CA, Mossuto MF, Meehan S, Gras SL, Christodoulou J, Anthony-Cahill SJ, Barker PD, Vendruscolo M, Dobson CM
- J Am Chem Soc 2011, 133, 14160-14163. DOI: 10.1021/ja2017703
- Enantioselective α-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts.
- Bigot A, Williamson AE, Gaunt MJ
- J Am Chem Soc 2011, 133, 13778-13781. DOI: 10.1021/ja206047h
- A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing.
- Lightfoot HL, Bugaut A, Armisen J, Lehrbach NJ, Miska EA, Balasubramanian S
- Biochemistry 2011, 50, 7514-7521. DOI: 10.1021/bi200851d
- A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium.
- Ramsay JP, Williamson NR, Spring DR, Salmond GP
- Proc Natl Acad Sci U S A 2011, 108, 14932-14937. DOI: 10.1073/pnas.1109169108
- Stereoselective Synthesis of Disubstituted Butadienes via Copper-Mediated Coupling of Alkenyl Silanes
- Blackwell DT, Galloway WRJD, Spring DR
- SYNLETT 2011, 0, 2140-2144. DOI: 10.1055/s-0030-1261150
- Controlling the transmission of stereochemical information through space in terphenyl-edged Fe4L6 cages.
- Meng W, Clegg JK, Thoburn JD, Nitschke JR
- J Am Chem Soc 2011, 133, 13652-13660. DOI: 10.1021/ja205254s
- Supramolecular composite materials from cucurbit[8]uril
- Coulston RJ, Jones ST, Lee TC, Appel E, Scherman OA
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- Strategies toward the synthesis of dictyodendrin B and dictyodendrin C via iterative metal-catalyzed C-H bond functionalization
- O'Hara F, Gaunt MJ
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- RInChIs and reactions
- Goodman JM
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- In silico inspired total synthesis of dolabriferol
- Currie RH, Goodman JM
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- Combining calculations and experiments in the analysis of NMR spectra: CP3, DP4 and beyond
- Goodman JM, Smith SG, Yuen SCH
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- Fragment based approach to targeting the Rad51:BRCA2 protein-protein interaction
- Coyne AG, Scott DE, Abell C, Marsh M, Hyvonen M, Blundell TL, Venkitaraman A
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology.
- Zhang AY, Bugaut A, Balasubramanian S
- Biochemistry 2011, 50, 7251-7258. DOI: 10.1021/bi200805j
- Synthesis of the macrocyclic core of leiodermatolide.
- Paterson I, Paquet T, Dalby SM
- Org Lett 2011, 13, 4398-4401. DOI: 10.1021/ol2017388
- Fluorescent sensing and discrimination of ATP and ADP based on a unique sandwich assembly of pyrene-adenine-pyrene.
- Xu Z, Spring DR, Yoon J
- Chem Asian J 2011, 6, 2114-2122. DOI: 10.1002/asia.201100120
- Piperazic acid-containing natural products: isolation, biological relevance and total synthesis.
- Oelke AJ, France DJ, Hofmann T, Wuitschik G, Ley SV
- Nat Prod Rep 2011, 28, 1445-1471. DOI: 10.1039/C1NP00041A
- The flow synthesis of heterocycles for natural product and medicinal chemistry applications.
- Baumann M, Baxendale IR, Ley SV
- Mol Divers 2011, 15, 613-630. DOI: 10.1007/s11030-010-9282-1
- Insights into the interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach
- Canales A, Rodriguez-Salarichs J, Trigili C, Nieto L, Coderch C, Andreu JM, Paterson I, Jimenez-Barbero J, Diaz JF
- ACS CHEM BIOL 2011, 3, 789-799. DOI: 10.1021/cb200099u
- Imaging sialylated tumor cell glycans in vivo.
- Neves AA, Stöckmann H, Harmston RR, Pryor HJ, Alam IS, Ireland-Zecchini H, Lewis DY, Lyons SK, Leeper FJ, Brindle KM
- FASEB J 2011, 25, 2528-2537. DOI: 10.1096/fj.10-178590
- Small molecules in biology.
- Tavassoli A, Hamilton AD, Spring DR
- Chem Soc Rev 2011, 40, 4269-4270. DOI: 10.1039/C1CS90028E
- Chemical genetics.
- O'Connor CJ, Laraia L, Spring DR
- Chem Soc Rev 2011, 40, 4332-4345. DOI: 10.1039/C1CS15053G
- Structure prediction, disorder and dynamics in a DMSO solvate of carbamazepine.
- Cruz-Cabeza AJ, Day GM, Jones W
- Phys Chem Chem Phys 2011, 0, 12808-12816. DOI: 10.1039/C1CP20927B
- Sequencing nucleic acids: from chemistry to medicine.
- Balasubramanian S
- Chem Commun (Camb) 2011, 47, 7281-7286. DOI: 10.1039/C1CC11078K
- Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.
- Baumann M, Baxendale IR, Kuratli C, Ley SV, Martin RE, Schneider J
- ACS Comb Sci 2011, 13, 405-413. DOI: 10.1021/co2000357
- The clerodane ring system: investigating the viability of a direct Diels-Alder approach.
- Merritt AT, Pouwer RH, Williams DJ, Williams CM, Ley SV
- Org Biomol Chem 2011, 9, 4745-4747. DOI: 10.1039/C1OB05422H
- (E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent.
- Stöckmann H, Neves AA, Day HA, Stairs S, Brindle KM, Leeper FJ
- Chem Commun (Camb) 2011, 47, 7203-7205. DOI: 10.1039/C1CC12161H
- A new enabling technology for convenient laboratory scale continuous flow processing at low temperatures.
- Browne DL, Baumann M, Harji BH, Baxendale IR, Ley SV
- Org Lett 2011, 13, 3312-3315. DOI: 10.1021/ol2010006
- Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells
- Wilmes A, O'Sullivan D, Chan A, Chandrahasen C, Paterson I, Northcote PT, La Flamme AC, Miller JH
- CANCER CHEMOTH PHARM 2011, 1, 117-126. DOI: 10.1007/s00280-010-1461-3
- Postpolymerization Modification of Hydroxyl-Functionalized Polymers with Isocyanates
- Biedermann F, Appel EA, del Barrio J, Gruendling T, Barner-Kowollik C, Scherman OA
- MACROMOLECULES 2011, 4, 4828-4835. DOI: 10.1021/ma2008018
- Extending the family of titanium heterometallic-oxo-alkoxy cages.
- Eslava S, Goodwill BP, McPartlin M, Wright DS
- Inorg Chem 2011, 50, 5655-5662. DOI: 10.1021/ic200350j
- Size selective supramolecular cages from aryl-bisimidazolium derivatives and cucurbit[8]uril.
- Jiao D, Biedermann F, Scherman OA
- Org Lett 2011, 13, 3044-3047. DOI: 10.1021/ol200911w
- Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis.
- Dias MV, Snee WC, Bromfield KM, Payne RJ, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL
- Biochem J 2011, 436, 729-739. DOI: 10.1042/BJ20110002
- Supramolecular Glycopolymers in Water: A Reversible Route Toward Multivalent Carbohydrate-Lectin Conjugates Using Cucurbit[8]uril
- Geng J, Biedermann F, Zayed JM, Tian F, Scherman OA
- MACROMOLECULES 2011, 3, 4276-4281. DOI: 10.1021/ma200343q
- Proton-driven switching between receptors for C60 and C70.
- Stefankiewicz AR, Tamanini E, Pantoş GD, Sanders JK
- Angew Chem Int Ed Engl 2011, 50, 5725-5728. DOI: 10.1002/anie.201100806
- Oxidative dehydrocoupling of N-H bonds using a redox-active main group superbase.
- Less RJ, Naseri V, McPartlin M, Wright DS
- Chem Commun (Camb) 2011, 47, 6129-6131. DOI: 10.1039/C1CC00053E
- 'On-demand' control of thermoresponsive properties of poly(N-isopropylacrylamide) with cucurbit[8]uril host-guest complexes.
- Rauwald U, del Barrio J, Loh XJ, Scherman OA
- Chem Commun (Camb) 2011, 47, 6000-6002. DOI: 10.1039/C1CC11214G
- Reversible anion-templated self-assembly of [2+2] and [3+3] metallomacrocycles containing a new dicopper(I) motif.
- Dry EF, Clegg JK, Breiner B, Whitaker DE, Stefak R, Nitschke JR
- Chem Commun (Camb) 2011, 47, 6021-6023. DOI: 10.1039/C1CC11206F
- Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme.
- Lupo G, Gestri G, O'Brien M, Denton RM, Chandraratna RA, Ley SV, Harris WA, Wilson SW
- Proc Natl Acad Sci U S A 2011, 108, 8698-8703. DOI: 10.1073/pnas.1103802108
- Precise subnanometer plasmonic junctions for SERS within gold nanoparticle assemblies using cucurbit[n]uril 'glue'.
- Taylor RW, Lee TC, Scherman OA, Esteban R, Aizpurua J, Huang FM, Baumberg JJ, Mahajan S
- ACS Nano 2011, 5, 3878-3887. DOI: 10.1021/nn200250v
- Nanoparticulate PdZn--pathways towards the synthetic control of nanosurface properties.
- Engels V, Jefferson DA, Benaskar F, Thüne PC, Berenguer-Murcia A, Johnson BF, Wheatley AE
- Nanotechnology 2011, 22, 205701 -. DOI: 10.1088/0957-4484/22/20/205701
- Cucurbituril: At the Interface of Small Molecule Host–Guest Chemistry and Dynamic Aggregates
- Das D, Scherman O
- Israel Journal of Chemistry 2011, 4, 537-550.
- Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins.
- Qi X, Loiseau F, Chan WL, Yan Y, Wei Z, Milroy LG, Myers RM, Ley SV, Read RJ, Carrell RW, Zhou A
- J Biol Chem 2011, 286, 16163-16173. DOI: 10.1074/jbc.M110.171082
- Experimental and database studies of three-centered halogen bonds with bifurcated acceptors present in molecular crystals, cocrystals and salts
- Cincic D, Friscic T, Jones W
- CRYSTENGCOMM 2011, 5, 3224-3231. DOI: 10.1039/C0CE00699H
- Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor
- Browne DL, Deadman BJ, Ashe R, Baxendale IR, Ley SV
- ORG PROCESS RES DEV 2011, 15, 693-697. DOI: 10.1021/op2000223
- The Serratia LuxR family regulator CarR 39006 activates transcription independently of cognate quorum sensing signals.
- Poulter S, Carlton TM, Spring DR, Salmond GP
- Mol Microbiol 2011, 80, 1120-1131. DOI: 10.1111/j.1365-2958.2011.07634.x
- Diversity-oriented synthesis of macrocyclic peptidomimetics.
- Isidro-Llobet A, Murillo T, Bello P, Cilibrizzi A, Hodgkinson JT, Galloway WR, Bender A, Welch M, Spring DR
- Proc Natl Acad Sci U S A 2011, 108, 6793-6798. DOI: 10.1073/pnas.1015267108
- An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals
- Baumann M, Baxendale IR, Ley SV, Nikbin N
- BEILSTEIN J ORG CHEM 2011, 7, 442-495. DOI: 10.3762/bjoc.7.57
- From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1.
- Śledź P, Stubbs CJ, Lang S, Yang YQ, McKenzie GJ, Venkitaraman AR, Hyvönen M, Abell C
- Angew Chem Int Ed Engl 2011, 50, 4003-4006. DOI: 10.1002/anie.201008019
- A quadruply-bonded [Cr2(guanidinate)4]4- tetraanion.
- Haywood J, Stokes FA, Less RJ, McPartlin M, Wheatley AE, Wright DS
- Chem Commun (Camb) 2011, 47, 4120-4122. DOI: 10.1039/C1CC10194C
- Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes.
- Dash J, Waller ZA, Pantoş GD, Balasubramanian S
- Chemistry 2011, 17, 4571-4581. DOI: 10.1002/chem.201003157
- Total synthesis of chloptosin: a dimeric cyclohexapeptide.
- Oelke AJ, Antonietti F, Bertone L, Cranwell PB, France DJ, Goss RJ, Hofmann T, Knauer S, Moss SJ, Skelton PC, Turner RM, Wuitschik G, Ley SV
- Chemistry 2011, 17, 4183-4194. DOI: 10.1002/chem.201003216
- A self-assembled M8L6 cubic cage that selectively encapsulates large aromatic guests.
- Meng W, Breiner B, Rissanen K, Thoburn JD, Clegg JK, Nitschke JR
- Angew Chem Int Ed Engl 2011, 50, 3479-3483. DOI: 10.1002/anie.201100193
- Lesser-Known Enabling Technologies for Organic Synthesis
- O'Brien M, Denton R, Ley SV
- SYNTHESIS-STUTTGART 2011, 3, 1157-1192. DOI: 10.1055/s-0030-1259979
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
- Balasubramanian S, Hurley LH, Neidle S
- Nat Rev Drug Discov 2011, 10, 261-275. DOI: 10.1038/nrd3428
- Recent developments in natural product synthesis using metal-catalysed C-H bond functionalisation.
- McMurray L, O'Hara F, Gaunt MJ
- Chem Soc Rev 2011, 40, 1885-1898. DOI: 10.1039/C1CS15013H
- Strategy Evolution in the Total Synthesis of Spirastrellolide A Methyl Ester
- Paterson I, Dalby SM, Maltas P
- ISR J CHEM 2011, 2, 406-419. DOI: 10.1002/ijch.201100007
- Effect of Fluorination on Molecular Conformation in the Solid State: Tuning the Conformation of Cocrystal Formers
- Friscic T, Reid DG, Day GM, Duer MJ, Jones W
- CRYST GROWTH DES 2011, 1, 972-981. DOI: 10.1021/cg1016388
- Enzyme synthesis and activity assay in microfluidic droplets on a chip
- Wu N, Courtois F, Surjadi R, Oakeshott J, Peat TS, Easton CJ, Abell C, Zhu YG
- ENG LIFE SCI 2011, 3, 157-164. DOI: 10.1002/elsc.201000043
- Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches.
- Cressina E, Chen L, Moulin M, Leeper FJ, Abell C, Smith AG
- Biochem Soc Trans 2011, 39, 652-657. DOI: 10.1042/BST0390652
- Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
- Paterson I, Dalby SM, Roberts JC, Naylor GJ, Guzmán EA, Isbrucker R, Pitts TP, Linley P, Divlianska D, Reed JK, Wright AE
- Angew Chem Int Ed Engl 2011, 50, 3219-3223. DOI: 10.1002/anie.201007719
- In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines.
- Tosin M, Demydchuk Y, Parascandolo JS, Per CB, Leeper FJ, Leadlay PF
- Chem Commun (Camb) 2011, 47, 3460-3462. DOI: 10.1039/C0CC05077F
- Quantitative tracking of the growth of individual algal cells in microdroplet compartments
- Pan J, Stephenson A, Abell C
- ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.
- Discovery of Linear Receptors for Multiple Dihydrogen Phosphate Ions Using Dynamic Combinatorial Chemistry
- Beeren SR, Sanders JKM
- J AM CHEM SOC 2011, 15, 3804-3807. DOI: 10.1021/ja200130h
- A Model for the Enantioselectivity of Imine Reactions Catalyzed by BINOL-Phosphoric Acid Catalysts
- Simon L, Goodman JM
- J ORG CHEM 2011, 8, 1775-1788. DOI: 10.1021/jo102410r
- Rational methods for the selection of diverse screening compounds.
- Huggins DJ, Venkitaraman AR, Spring DR
- ACS Chem Biol 2011, 6, 208-217. DOI: 10.1021/cb100420r
- Diastereoselective chain-elongation reactions using microreactors for applications in complex molecule assembly.
- Carter CF, Lange H, Sakai D, Baxendale IR, Ley SV
- Chemistry 2011, 17, 3398-3405. DOI: 10.1002/chem.201003148
- A Self-Assembled M(8) L(6) Cubic Cage that Selectively Encapsulates Large Aromatic Guests.
- Meng W, Breiner B, Rissanen K, Thoburn JD, Clegg JK, Nitschke JR
- Angew Chem Int Ed Engl 2011, -. DOI: 10.1002/anie.201101114
- A dynamic covalent, luminescent metallopolymer that undergoes sol-to-gel transition on temperature rise.
- de Hatten X, Bell N, Yufa N, Christmann G, Nitschke JR
- J Am Chem Soc 2011, 133, 3158-3164. DOI: 10.1021/ja110575s
- Exploring the Formation Pathways of Donor-Acceptor Catenanes in Aqueous Dynamic Combinatorial Libraries
- Cougnon FBL, Au-Yeung HY, Pantos GD, Sanders JKM
- J AM CHEM SOC 2011, 15, 3198-3207. DOI: 10.1021/ja111407m
- Observation of a two-dimensional halogen-bonded cocrystal at sub-monolayer coverage using synchrotron X-ray diffraction.
- Paterson I, Doughty VASN, McLeod MD, Trieselmann T

