Department of Chemistry

Synthesis Publications (2011)


Stereocontrolled total synthesis of (+)-concanamycin F: the strategic use of boron-mediated aldol reactions of chiral ketones
Paterson I, Doughty VASN, McLeod MD, Trieselmann T
TETRAHEDRON 2011, 0, 10119-10128. DOI: 10.1016/j.tet.2011.09.012


Decoding genomes at high speed: implications for science and medicine.
Balasubramanian S
Angew Chem Int Ed Engl 2011, 50, 12406-12410. DOI: 10.1002/anie.201106707


A cocrystal strategy to tune the luminescent properties of stilbene-type organic solid-state materials.
Yan D, Delori A, Lloyd GO, Friščić T, Day GM, Jones W, Lu J, Wei M, Evans DG, Duan X
Angew Chem Int Ed Engl 2011, 2, 12483-12486. DOI: 10.1002/anie.201106391


The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
Roper KA, Lange H, Polyzos A, Berry MB, Baxendale IR, Ley SV
BEILSTEIN J ORG CHEM 2011, 7, 1648-1655. DOI: 10.3762/bjoc.7.194


Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site (vol 19, pg 1691, 2011)
Bolanos-Garcia VM, Lischetti T, Matak-Vinkovic D, Cota E, Simpson PJ, Chirgadze DY, Spring DR, Robinson CV, Nilsson J, Blundell TL
STRUCTURE 2011, 0, 1895-1895. DOI: 10.1016/j.str.2011.11.011


Subcomponent Self-Assembly and Guest-Binding Properties of Face-Capped Fe(4)L(4)(8+) Capsules.
Bilbeisi RA, Clegg JK, Elgrishi N, Hatten XD, Devillard M, Breiner B, Mal P, Nitschke JR
J Am Chem Soc 2011, -. DOI: 10.1021/ja2092272


2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa.
Ha DG, Merritt JH, Hampton TH, Hodgkinson JT, Janecek M, Spring DR, Welch M, O'Toole GA
J Bacteriol 2011, 193, 6770-6780. DOI: 10.1128/JB.05929-11


Aryl-aryl bond formation by the fluoride-free cross-coupling of aryldisiloxanes with aryl bromides.
Boehner CM, Frye EC, O'Connell KM, Galloway WR, Sore HF, Dominguez PG, Norton D, Hulcoop DG, Owen M, Turner G, Crawford C, Horsley H, Spring DR
Chemistry 2011, 17, 13230-13239. DOI: 10.1002/chem.201102285


Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site.
Bolanos-Garcia VM, Lischetti T, Matak-Vinković D, Cota E, Simpson PJ, Chirgadze DY, Spring DR, Robinson CV, Nilsson J, Blundell TL
Structure 2011, 19, 1691-1700. DOI: 10.1016/j.str.2011.09.017


Exploring isonitrile-based click chemistry for ligation with biomolecules.
Stöckmann H, Neves AA, Stairs S, Brindle KM, Leeper FJ
Org Biomol Chem 2011, 9, 7303-7305. DOI: 10.1039/C1OB06424J


PNA to DNA to microarray decoding facilitates ligand discovery.
Galloway WR, Spring DR
Chem Biol 2011, 18, 1209-1210. DOI: 10.1016/j.chembiol.2011.10.002


A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands
Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao HB
NAT CHEM 2011, 3, 782-787. DOI: 10.1038/NCHEM.1126


Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery.
Philpott M, Yang J, Tumber T, Fedorov O, Uttarkar S, Filippakopoulos P, Picaud S, Keates T, Felletar I, Ciulli A, Knapp S, Heightman TD
Mol Biosyst 2011, 7, 2899-2908. DOI: 10.1039/C1MB05099K


Transition metal complexes of the pentacyanocyclopentadienide anion.
Less RJ, Wilson TC, McPartlin M, Wood PT, Wright DS
Chem Commun (Camb) 2011, 47, 10007-10009. DOI: 10.1039/C1CC13021H


Metastability of native proteins and the phenomenon of amyloid formation.
Baldwin AJ, Knowles TP, Tartaglia GG, Fitzpatrick AW, Devlin GL, Shammas SL, Waudby CA, Mossuto MF, Meehan S, Gras SL, Christodoulou J, Anthony-Cahill SJ, Barker PD, Vendruscolo M, Dobson CM
J Am Chem Soc 2011, 133, 14160-14163. DOI: 10.1021/ja2017703


Enantioselective α-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts.
Bigot A, Williamson AE, Gaunt MJ
J Am Chem Soc 2011, 133, 13778-13781. DOI: 10.1021/ja206047h


A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing.
Lightfoot HL, Bugaut A, Armisen J, Lehrbach NJ, Miska EA, Balasubramanian S
Biochemistry 2011, 50, 7514-7521. DOI: 10.1021/bi200851d


A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium.
Ramsay JP, Williamson NR, Spring DR, Salmond GP
Proc Natl Acad Sci U S A 2011, 108, 14932-14937. DOI: 10.1073/pnas.1109169108


Stereoselective Synthesis of Disubstituted Butadienes via Copper-Mediated Coupling of Alkenyl Silanes
Blackwell DT, Galloway WRJD, Spring DR
SYNLETT 2011, 0, 2140-2144. DOI: 10.1055/s-0030-1261150


Controlling the transmission of stereochemical information through space in terphenyl-edged Fe4L6 cages.
Meng W, Clegg JK, Thoburn JD, Nitschke JR
J Am Chem Soc 2011, 133, 13652-13660. DOI: 10.1021/ja205254s


Supramolecular composite materials from cucurbit[8]uril
Coulston RJ, Jones ST, Lee TC, Appel E, Scherman OA
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


Strategies toward the synthesis of dictyodendrin B and dictyodendrin C via iterative metal-catalyzed C-H bond functionalization
O'Hara F, Gaunt MJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


RInChIs and reactions
Goodman JM
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


In silico inspired total synthesis of dolabriferol
Currie RH, Goodman JM
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


Combining calculations and experiments in the analysis of NMR spectra: CP3, DP4 and beyond
Goodman JM, Smith SG, Yuen SCH
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


Fragment based approach to targeting the Rad51:BRCA2 protein-protein interaction
Coyne AG, Scott DE, Abell C, Marsh M, Hyvonen M, Blundell TL, Venkitaraman A
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology.
Zhang AY, Bugaut A, Balasubramanian S
Biochemistry 2011, 50, 7251-7258. DOI: 10.1021/bi200805j


Synthesis of the macrocyclic core of leiodermatolide.
Paterson I, Paquet T, Dalby SM
Org Lett 2011, 13, 4398-4401. DOI: 10.1021/ol2017388


Fluorescent sensing and discrimination of ATP and ADP based on a unique sandwich assembly of pyrene-adenine-pyrene.
Xu Z, Spring DR, Yoon J
Chem Asian J 2011, 6, 2114-2122. DOI: 10.1002/asia.201100120


Piperazic acid-containing natural products: isolation, biological relevance and total synthesis.
Oelke AJ, France DJ, Hofmann T, Wuitschik G, Ley SV
Nat Prod Rep 2011, 28, 1445-1471. DOI: 10.1039/C1NP00041A


The flow synthesis of heterocycles for natural product and medicinal chemistry applications.
Baumann M, Baxendale IR, Ley SV
Mol Divers 2011, 15, 613-630. DOI: 10.1007/s11030-010-9282-1


Insights into the interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach
Canales A, Rodriguez-Salarichs J, Trigili C, Nieto L, Coderch C, Andreu JM, Paterson I, Jimenez-Barbero J, Diaz JF
ACS CHEM BIOL 2011, 3, 789-799. DOI: 10.1021/cb200099u


Imaging sialylated tumor cell glycans in vivo.
Neves AA, Stöckmann H, Harmston RR, Pryor HJ, Alam IS, Ireland-Zecchini H, Lewis DY, Lyons SK, Leeper FJ, Brindle KM
FASEB J 2011, 25, 2528-2537. DOI: 10.1096/fj.10-178590


Small molecules in biology.
Tavassoli A, Hamilton AD, Spring DR
Chem Soc Rev 2011, 40, 4269-4270. DOI: 10.1039/C1CS90028E


Chemical genetics.
O'Connor CJ, Laraia L, Spring DR
Chem Soc Rev 2011, 40, 4332-4345. DOI: 10.1039/C1CS15053G


Structure prediction, disorder and dynamics in a DMSO solvate of carbamazepine.
Cruz-Cabeza AJ, Day GM, Jones W
Phys Chem Chem Phys 2011, 0, 12808-12816. DOI: 10.1039/C1CP20927B


Sequencing nucleic acids: from chemistry to medicine.
Balasubramanian S
Chem Commun (Camb) 2011, 47, 7281-7286. DOI: 10.1039/C1CC11078K


Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.
Baumann M, Baxendale IR, Kuratli C, Ley SV, Martin RE, Schneider J
ACS Comb Sci 2011, 13, 405-413. DOI: 10.1021/co2000357


The clerodane ring system: investigating the viability of a direct Diels-Alder approach.
Merritt AT, Pouwer RH, Williams DJ, Williams CM, Ley SV
Org Biomol Chem 2011, 9, 4745-4747. DOI: 10.1039/C1OB05422H


(E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent.
Stöckmann H, Neves AA, Day HA, Stairs S, Brindle KM, Leeper FJ
Chem Commun (Camb) 2011, 47, 7203-7205. DOI: 10.1039/C1CC12161H


A new enabling technology for convenient laboratory scale continuous flow processing at low temperatures.
Browne DL, Baumann M, Harji BH, Baxendale IR, Ley SV
Org Lett 2011, 13, 3312-3315. DOI: 10.1021/ol2010006


Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells
Wilmes A, O'Sullivan D, Chan A, Chandrahasen C, Paterson I, Northcote PT, La Flamme AC, Miller JH
CANCER CHEMOTH PHARM 2011, 1, 117-126. DOI: 10.1007/s00280-010-1461-3


Postpolymerization Modification of Hydroxyl-Functionalized Polymers with Isocyanates
Biedermann F, Appel EA, del Barrio J, Gruendling T, Barner-Kowollik C, Scherman OA
MACROMOLECULES 2011, 4, 4828-4835. DOI: 10.1021/ma2008018


Extending the family of titanium heterometallic-oxo-alkoxy cages.
Eslava S, Goodwill BP, McPartlin M, Wright DS
Inorg Chem 2011, 50, 5655-5662. DOI: 10.1021/ic200350j


Size selective supramolecular cages from aryl-bisimidazolium derivatives and cucurbit[8]uril.
Jiao D, Biedermann F, Scherman OA
Org Lett 2011, 13, 3044-3047. DOI: 10.1021/ol200911w


Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis.
Dias MV, Snee WC, Bromfield KM, Payne RJ, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL
Biochem J 2011, 436, 729-739. DOI: 10.1042/BJ20110002


Supramolecular Glycopolymers in Water: A Reversible Route Toward Multivalent Carbohydrate-Lectin Conjugates Using Cucurbit[8]uril
Geng J, Biedermann F, Zayed JM, Tian F, Scherman OA
MACROMOLECULES 2011, 3, 4276-4281. DOI: 10.1021/ma200343q


Proton-driven switching between receptors for C60 and C70.
Stefankiewicz AR, Tamanini E, Pantoş GD, Sanders JK
Angew Chem Int Ed Engl 2011, 50, 5725-5728. DOI: 10.1002/anie.201100806


Oxidative dehydrocoupling of N-H bonds using a redox-active main group superbase.
Less RJ, Naseri V, McPartlin M, Wright DS
Chem Commun (Camb) 2011, 47, 6129-6131. DOI: 10.1039/C1CC00053E


'On-demand' control of thermoresponsive properties of poly(N-isopropylacrylamide) with cucurbit[8]uril host-guest complexes.
Rauwald U, del Barrio J, Loh XJ, Scherman OA
Chem Commun (Camb) 2011, 47, 6000-6002. DOI: 10.1039/C1CC11214G


Reversible anion-templated self-assembly of [2+2] and [3+3] metallomacrocycles containing a new dicopper(I) motif.
Dry EF, Clegg JK, Breiner B, Whitaker DE, Stefak R, Nitschke JR
Chem Commun (Camb) 2011, 47, 6021-6023. DOI: 10.1039/C1CC11206F


Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme.
Lupo G, Gestri G, O'Brien M, Denton RM, Chandraratna RA, Ley SV, Harris WA, Wilson SW
Proc Natl Acad Sci U S A 2011, 108, 8698-8703. DOI: 10.1073/pnas.1103802108


Precise subnanometer plasmonic junctions for SERS within gold nanoparticle assemblies using cucurbit[n]uril 'glue'.
Taylor RW, Lee TC, Scherman OA, Esteban R, Aizpurua J, Huang FM, Baumberg JJ, Mahajan S
ACS Nano 2011, 5, 3878-3887. DOI: 10.1021/nn200250v


Nanoparticulate PdZn--pathways towards the synthetic control of nanosurface properties.
Engels V, Jefferson DA, Benaskar F, Thüne PC, Berenguer-Murcia A, Johnson BF, Wheatley AE
Nanotechnology 2011, 22, 205701 -. DOI: 10.1088/0957-4484/22/20/205701


Cucurbituril: At the Interface of Small Molecule Host–Guest Chemistry and Dynamic Aggregates
Das D, Scherman O
Israel Journal of Chemistry 2011, 4, 537-550.


Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins.
Qi X, Loiseau F, Chan WL, Yan Y, Wei Z, Milroy LG, Myers RM, Ley SV, Read RJ, Carrell RW, Zhou A
J Biol Chem 2011, 286, 16163-16173. DOI: 10.1074/jbc.M110.171082


Experimental and database studies of three-centered halogen bonds with bifurcated acceptors present in molecular crystals, cocrystals and salts
Cincic D, Friscic T, Jones W
CRYSTENGCOMM 2011, 5, 3224-3231. DOI: 10.1039/C0CE00699H


Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor
Browne DL, Deadman BJ, Ashe R, Baxendale IR, Ley SV
ORG PROCESS RES DEV 2011, 15, 693-697. DOI: 10.1021/op2000223


The Serratia LuxR family regulator CarR 39006 activates transcription independently of cognate quorum sensing signals.
Poulter S, Carlton TM, Spring DR, Salmond GP
Mol Microbiol 2011, 80, 1120-1131. DOI: 10.1111/j.1365-2958.2011.07634.x


Diversity-oriented synthesis of macrocyclic peptidomimetics.
Isidro-Llobet A, Murillo T, Bello P, Cilibrizzi A, Hodgkinson JT, Galloway WR, Bender A, Welch M, Spring DR
Proc Natl Acad Sci U S A 2011, 108, 6793-6798. DOI: 10.1073/pnas.1015267108


An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals
Baumann M, Baxendale IR, Ley SV, Nikbin N
BEILSTEIN J ORG CHEM 2011, 7, 442-495. DOI: 10.3762/bjoc.7.57


From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1.
Śledź P, Stubbs CJ, Lang S, Yang YQ, McKenzie GJ, Venkitaraman AR, Hyvönen M, Abell C
Angew Chem Int Ed Engl 2011, 50, 4003-4006. DOI: 10.1002/anie.201008019


A quadruply-bonded [Cr2(guanidinate)4]4- tetraanion.
Haywood J, Stokes FA, Less RJ, McPartlin M, Wheatley AE, Wright DS
Chem Commun (Camb) 2011, 47, 4120-4122. DOI: 10.1039/C1CC10194C


Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes.
Dash J, Waller ZA, Pantoş GD, Balasubramanian S
Chemistry 2011, 17, 4571-4581. DOI: 10.1002/chem.201003157


Total synthesis of chloptosin: a dimeric cyclohexapeptide.
Oelke AJ, Antonietti F, Bertone L, Cranwell PB, France DJ, Goss RJ, Hofmann T, Knauer S, Moss SJ, Skelton PC, Turner RM, Wuitschik G, Ley SV
Chemistry 2011, 17, 4183-4194. DOI: 10.1002/chem.201003216


A self-assembled M8L6 cubic cage that selectively encapsulates large aromatic guests.
Meng W, Breiner B, Rissanen K, Thoburn JD, Clegg JK, Nitschke JR
Angew Chem Int Ed Engl 2011, 50, 3479-3483. DOI: 10.1002/anie.201100193


Lesser-Known Enabling Technologies for Organic Synthesis
O'Brien M, Denton R, Ley SV
SYNTHESIS-STUTTGART 2011, 3, 1157-1192. DOI: 10.1055/s-0030-1259979


Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Balasubramanian S, Hurley LH, Neidle S
Nat Rev Drug Discov 2011, 10, 261-275. DOI: 10.1038/nrd3428


Recent developments in natural product synthesis using metal-catalysed C-H bond functionalisation.
McMurray L, O'Hara F, Gaunt MJ
Chem Soc Rev 2011, 40, 1885-1898. DOI: 10.1039/C1CS15013H


Strategy Evolution in the Total Synthesis of Spirastrellolide A Methyl Ester
Paterson I, Dalby SM, Maltas P
ISR J CHEM 2011, 2, 406-419. DOI: 10.1002/ijch.201100007


Effect of Fluorination on Molecular Conformation in the Solid State: Tuning the Conformation of Cocrystal Formers
Friscic T, Reid DG, Day GM, Duer MJ, Jones W
CRYST GROWTH DES 2011, 1, 972-981. DOI: 10.1021/cg1016388


Enzyme synthesis and activity assay in microfluidic droplets on a chip
Wu N, Courtois F, Surjadi R, Oakeshott J, Peat TS, Easton CJ, Abell C, Zhu YG
ENG LIFE SCI 2011, 3, 157-164. DOI: 10.1002/elsc.201000043


Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches.
Cressina E, Chen L, Moulin M, Leeper FJ, Abell C, Smith AG
Biochem Soc Trans 2011, 39, 652-657. DOI: 10.1042/BST0390652


Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
Paterson I, Dalby SM, Roberts JC, Naylor GJ, Guzmán EA, Isbrucker R, Pitts TP, Linley P, Divlianska D, Reed JK, Wright AE
Angew Chem Int Ed Engl 2011, 50, 3219-3223. DOI: 10.1002/anie.201007719


In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines.
Tosin M, Demydchuk Y, Parascandolo JS, Per CB, Leeper FJ, Leadlay PF
Chem Commun (Camb) 2011, 47, 3460-3462. DOI: 10.1039/C0CC05077F


Quantitative tracking of the growth of individual algal cells in microdroplet compartments
Pan J, Stephenson A, Abell C
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2011, 0, -.


Discovery of Linear Receptors for Multiple Dihydrogen Phosphate Ions Using Dynamic Combinatorial Chemistry
Beeren SR, Sanders JKM
J AM CHEM SOC 2011, 15, 3804-3807. DOI: 10.1021/ja200130h


A Model for the Enantioselectivity of Imine Reactions Catalyzed by BINOL-Phosphoric Acid Catalysts
Simon L, Goodman JM
J ORG CHEM 2011, 8, 1775-1788. DOI: 10.1021/jo102410r


Rational methods for the selection of diverse screening compounds.
Huggins DJ, Venkitaraman AR, Spring DR
ACS Chem Biol 2011, 6, 208-217. DOI: 10.1021/cb100420r


Diastereoselective chain-elongation reactions using microreactors for applications in complex molecule assembly.
Carter CF, Lange H, Sakai D, Baxendale IR, Ley SV
Chemistry 2011, 17, 3398-3405. DOI: 10.1002/chem.201003148


A Self-Assembled M(8) L(6) Cubic Cage that Selectively Encapsulates Large Aromatic Guests.
Meng W, Breiner B, Rissanen K, Thoburn JD, Clegg JK, Nitschke JR
Angew Chem Int Ed Engl 2011, -. DOI: 10.1002/anie.201101114


A dynamic covalent, luminescent metallopolymer that undergoes sol-to-gel transition on temperature rise.
de Hatten X, Bell N, Yufa N, Christmann G, Nitschke JR
J Am Chem Soc 2011, 133, 3158-3164. DOI: 10.1021/ja110575s


Exploring the Formation Pathways of Donor-Acceptor Catenanes in Aqueous Dynamic Combinatorial Libraries
Cougnon FBL, Au-Yeung HY, Pantos GD, Sanders JKM
J AM CHEM SOC 2011, 15, 3198-3207. DOI: 10.1021/ja111407m


Observation of a two-dimensional halogen-bonded cocrystal at sub-monolayer coverage using synchrotron X-ray diffraction.
Clarke SM, Friščić T, Jones W, Mandal A, Sun C, Parker JE
2011, 47, 2526-2528. DOI: 10.1039/C0CC04400H


Catalytic dehydrocoupling of Me2NHBH3 with Al(NMe2)3.
Cowley HJ, Holt MS, Melen RL, Rawson JM, Wright DS
Chem Commun (Camb) 2011, 47, 2682-2684. DOI: 10.1039/C0CC05294A


Dynamic Combinatorial Donor-Acceptor Catenanes in Water: Access to Unconventional and Unexpected Structures
Au-Yeung HY, Pantos GD, Sanders JKM
J ORG CHEM 2011, 76, 1257-1268. DOI: 10.1021/jo101981p


G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.
McLuckie KI, Waller ZA, Sanders DA, Alves D, Rodriguez R, Dash J, McKenzie GJ, Venkitaraman AR, Balasubramanian S
J Am Chem Soc 2011, 133, 2658-2663. DOI: 10.1021/ja109474c


Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls.
Kenwright JL, Galloway WR, Blackwell DT, Isidro-Llobet A, Hodgkinson J, Wortmann L, Bowden SD, Welch M, Spring DR
Chemistry 2011, 2981-2986. DOI: 10.1002/chem.201002093


SYNTHESIS OF HIGHLY SUBSTITUTED NITROPYRROLIDINES, NITROPYRROLIZINES AND NITROPYRROLES VIA MULTICOMPONENT-MULTISTEP SEQUENCES WITHIN A FLOW REACTOR
Baumann M, Baxendale IR, Kirschning A, Ley SV, Wegner J
HETEROCYCLES 2011, 82, 1297-+. DOI: 10.3987/COM-10-S(E)77


An unexpected dependence on the SnII base; reactions of Sn(NR2)2 with aromatic dithiols.
Melen RL, McPartlin M, Wright DS
Dalton Trans 2011, 40, 1649-1651. DOI: 10.1039/C0DT01690J


Peptide separation through a CB[8]-mediated supramolecular trap-and-release process.
Tian F, Cziferszky M, Jiao D, Wahlström K, Geng J, Scherman OA
Electrochemistry, Magnetic Resonance Spectroscopy, Microscopy, Fluorescence, Peptides, Spectrometry, Mass, Electrospray Ionization, Tryptophan 2011, 27, 1387-1390. DOI: 10.1021/la104346k


Monitoring a reaction at submillisecond resolution in picoliter volumes.
Huebner AM, Abell C, Huck WT, Baroud CN, Hollfelder F
Anal Chem 2011, 83, 1462-1468. DOI: 10.1021/ac103234a


Confinement of halide ions within homologous inverse coordination hosts; modification of halide-ion selectivity.
García F, Less RJ, McPartlin M, Michalski A, Mulvey RE, Naseri V, Stead ML, Morán de Vega A, Wright DS
2011, 47, 1821-1823. DOI: 10.1039/C0CC04483K


Photocatalytic H2 evolution from neutral water with a molecular cobalt catalyst on a dye-sensitised TiO2 nanoparticle.
Lakadamyali F, Reisner E
Chem Commun (Camb) 2011, 47, 1695-1697. DOI: 10.1039/C0CC04658B


Controlling the contents of microdroplets by exploiting the permeability of PDMS
Shim J, Patil SN, Hodgkinson JT, Bowden SD, Spring DR, Welch M, Huck WTS, Hollfelder F, Abell C
Lab Chip 2011, 4, 1132-1137. DOI: 10.1039/C0LC00615G


Better leads come from diversity
Galloway WRJD, Spring DR
NATURE 2011, 43-43.


Drug discovery: A question of library design.
Hajduk PJ, Galloway WR, Spring DR
Nature 2011, 470, 42-43. DOI: 10.1038/470042a


Palladium(II)-catalyzed C-H bond arylation of electron-deficient arenes at room temperature.
Tredwell MJ, Gulias M, Bremeyer NG, Johansson CC, Collins BS, Gaunt MJ
Angew Chem Int Ed Engl 2011, 50, 1076-1079. DOI: 10.1002/anie.201005990


The continuous-flow synthesis of carboxylic acids using CO2 in a tube-in-tube gas permeable membrane reactor.
Polyzos A, O'Brien M, Petersen TP, Baxendale IR, Ley SV
Angew Chem Int Ed Engl 2011, 50, 1190-1193. DOI: 10.1002/anie.201006618


Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
Paterson I, Naylor GJ, Gardner NM, Guzmán E, Wright AE
Chem Asian J 2011, 6, 459-473. DOI: 10.1002/asia.201000541


Induction-driven stabilization of the anion-π interaction in electron-rich aromatics as the key to fluoride inclusion in imidazolium-cage receptors.
Xu Z, Singh NJ, Kim SK, Spring DR, Kim KS, Yoon J
Chemistry 2011, 17, 1163-1170. DOI: 10.1002/chem.201002105


Vinyldisiloxanes: their synthesis, cross coupling and applications.
Sore HF, Boehner CM, Laraia L, Logoteta P, Prestinari C, Scott M, Williams K, Galloway WR, Spring DR
Cross-Linking Reagents, Cyclization, Fluorides, Molecular Structure, Silanes, Stereoisomerism, Vinyl Compounds 2011, 9, 504-515. DOI: 10.1039/C0OB00338G


Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor.
Martin LJ, Marzinzik AL, Ley SV, Baxendale IR
Org Lett 2011, 13, 320-323. DOI: 10.1021/ol1027927


Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways.
Galloway WR, Hodgkinson JT, Bowden SD, Welch M, Spring DR
Acyl-Butyrolactones, Bacterial Proteins, Carbon-Sulfur Lyases, Gram-Negative Bacteria, Homoserine, Lactones, Quorum Sensing, Repressor Proteins, Trans-Activators 2011, 111, 28-67. DOI: 10.1021/cr100109t


Copper(II)-catalyzed meta-selective direct arylation of α-aryl carbonyl compounds.
Duong HA, Gilligan RE, Cooke ML, Phipps RJ, Gaunt MJ
Benzene, Carbon, Catalysis, Copper, Hydrogen, Iodine, Ketones 2011, 50, 463-466. DOI: 10.1002/anie.201004704


A highly para-selective copper(II)-catalyzed direct arylation of aniline and phenol derivatives.
Ciana CL, Phipps RJ, Brandt JR, Meyer FM, Gaunt MJ
Aniline Compounds, Catalysis, Copper, Iodine, Phenol 2011, 50, 458-462. DOI: 10.1002/anie.201004703


Total syntheses of subereamollines A and B.
Shearman JW, Myers RM, Brenton JD, Ley SV
Carbamates, Isoxazoles, Molecular Structure, Spiro Compounds, Stereoisomerism 2011, 9, 62-65. DOI: 10.1039/C0OB00636J


Supramolecular gold nanoparticle-polymer composites formed in water with cucurbit[8]uril.
Coulston RJ, Jones ST, Lee TC, Appel EA, Scherman OA
Bridged Compounds, Gold, Imidazoles, Macromolecular Substances, Metal Nanoparticles, Models, Molecular, Molecular Structure, Particle Size, Polymers, Solubility, Water 2011, 47, 164-166. DOI: 10.1039/C0CC03250F


Encapsulation, storage and controlled release of sulfur hexafluoride from a metal-organic capsule.
Riddell IA, Smulders MM, Clegg JK, Nitschke JR
Chem Commun (Camb) 2011, 47, 457-459. DOI: 10.1039/C0CC02573A


Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues.
Hodgkinson JT, Galloway WR, Saraf S, Baxendale IR, Ley SV, Ladlow M, Welch M, Spring DR
Org Biomol Chem 2011, 9, 57-61. DOI: 10.1039/C0OB00652A


Total synthesis of iso- and bongkrekic acids: natural antibiotics displaying potent antiapoptotic properties.
Français A, Leyva-Pérez A, Etxebarria-Jardi G, Peña J, Ley SV
Chemistry 2011, 17, 329-343. DOI: 10.1002/chem.201002380


The two faces of phosphorus.
Nitschke JR
Nat Chem 2011, 3, 90 -. DOI: 10.1038/nchem.944


The Lab of the Future The importance of remote monitoring and control
Hopkin MD, Baxendale IR, Ley SV
CHIM OGGI 2011, 29, 28-+.


A chelating dendritic ligand capped quantum dot: preparation, surface passivation, bioconjugation and specific DNA detection.
Zhou D, Li Y, Hall EA, Abell C, Klenerman D
Cadmium Compounds, Chelating Agents, DNA, DNA Probes, Dendrimers, Fluorescence Resonance Energy Transfer, Ligands, Nucleic Acid Hybridization, Quantum Dots, Selenium Compounds, Spectrometry, Fluorescence, Sulfides, Zinc Compounds 2011, 3, 201-211. DOI: 10.1039/C0NR00462F


Thermodynamics of Supramolecular Naphthalenediimide Nanotube Formation: The Influence of Solvents, Side Chains, and Guest Templates
Nandhini Ponnuswamy, G Dan Pantoş, Maarten M J Smulders, and Jeremy K M Sanders
Journal_of_the_American_Chemical_Society DOI: 10.1021/ja2088647


Copper-free click-a promising tool for pre-targeted PET imaging
Helen L Evans, Rozanna L Slade, Laurence Carroll, Graham Smith, Quang-De Nguyen, Lisa Iddon, Nazila Kamaly, Henning Stockmann, Finian J Leeper, Eric O Aboagye, Alan C Spivey
Chemical_Communications DOI: 10.1039/C1CC16220A


Probed by Electronic Structure Calculations, and by NMR and IR Spectroscopy
Damian M Grainger, Alison Campbell Smith, Mark A Vincent, Ian H Hillier, Andrew E H Wheatley and Jonathan Clayden
European_Journal_of_Organic_Chemistry DOI: 10.1002/ejoc.201101475


Deprotonative Metalation of Chloro- and Bromopyridines Using Amido-Based Bimetallic Species and Regioselectivity-Computed CH Acidity Relationships
Dr Katia Snégaroff, Tan Tai Nguyen, Nada Marquise, Dr Yury S Halauko, Philip J Harford, Dr Thierry Roisnel, Dr Vadim E Matulis, Prof Oleg A Ivashkevich, Dr Floris Chevallier, Dr Andrew E H Wheatley, Dr Philippe C Gros and Prof Florence Mongin
Chemistry_-_A_European_Journal DOI: 10.1002/chem.201101993


Quantitative tracking of the growth of individual algal cells in microdroplet compartments
Jie Pan, Anna L Stephenson, Elena Kazamia, Wilhelm T S Huck, John S Dennis, Alison G Smith, Chris Abell
Integrative_Biology DOI: 10.1039/C1IB00033K


Teflon AF-2400 mediated gas-liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration
Peter Koos, Ulrike Gross, Anastasios Polyzos, Matthew O'Brien, Ian Baxendale, Steven V Ley
Organic_and_Biomolecular_Chemistry DOI: 10.1039/C1OB06017A


Ligand Effects in the Formation of Tertiary Carbanions from Substituted Tertiary Aromatic Amides
Alison Campbell Smith, Morgan Donnard, Joanna Haywood, Mary McPartlin, Mark A Vincent, Ian H Hillier, Jonathan Clayden and Andrew E H Wheatley
Chemistry_-_A_European_Journal DOI: 10.1002/chem.201100240


Diastereoselective Chain-Elongation Reactions Using Microreactors for Applications in Complex Molecule Assembly
Catherine F Carter, Heiko Lange, Daiki Sakai, Ian R Baxendale and Steven V Ley
Chemistry_-_A_European_Journal DOI: 10.1002/chem.201003148


A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles
Catherine J Smith, Nikzad Nikbin, Steven V Ley, Heiko Lange, Ian R Baxendale
Organic_and_Biomolecular_Chemistry DOI: 10.1039/C0OB00815J


Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent
Catherine J Smith, Christopher D Smith, Nikzad Nikbin, Steven V Ley, Ian R Baxendale
Organic_and_Biomolecular_Chemistry DOI: 10.1039/C0OB00813C


Robust routes for the synthesis of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity
Hodgkinson JT, Galloway WRJD, Casoli M, Keane H, Su X, Salmond GPC, Welch M, Spring DR
Tetrahedron Letters 2011, 1, -.


Regioselectivity in Thermal Rhodium(II)-Catalysed Büchner-Type Reactions of Substituted Aryl Halides: Studies towards the Synthesis of Halide-Substituted Cycloheptatrienes
Wyatt EE, Galloway WRJD, Spring DR
Synlett 2011, 0, -.


Lesser-known enabling technologies for organic synthesis
O'Brien M, Denton R, Ley SV
Synthesis 2011, 1157-1192.


Cobalt catalyzed carbon nanotube growth on graphitic paper supports
Engels V, Geng J, Jones GM, Elliott JA, Wheatley AEH, Boss SR
Current Nanoscience 2011, 0, 315-322.


Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae
Smith JS, Chen Q, Yatsunyk LA, Nicoludis JM, Garcia MS, Kranaster R, Balasubramanian S, Monchaud D, Teulade-Fichou M-P, Abramowitz L, Schultz DC, Johnson FB
Nature Structural and Molecular Biology 2011, 6, -.


Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae
Smith JS, Chen Q, Yatsunyk LA, Nicoludis JM, Garcia MS, Kranaster R, Balasubramanian S, Monchaud D, Teulade-Fichou M-P, Abramowitz L, Schultz DC, Johnson FB
Nature Structural and Molecular Biology 2011, 478-486.


Assembly of the first fullerene-type metal-organic frameworks using a planar five-fold coordination node
Bacsa J, Less RJ, Skelton HE, Soracevic Z, Steiner A, Wilson TC, Wood PT, Wright DS
Angewandte Chemie - International Edition 2011, 50, 8279-8282.


A quadruply-bonded [Cr 2(guanidinate) 4] 4- tetraanion
Haywood J, Stokes FA, Less RJ, McPartlin M, Wheatley AEH, Wright DS
Chemical Communications 2011, 4120-4122.


Metal and redox selectivity of protoporphyrin binding to the heme chaperone CcmE
Harvat EM, Daltrop O, Sobott F, Moreau M, Barker PD, Stevens JM, Ferguson SJ
METALLOMICS 2011, 0, 363-368. DOI: 10.1039/c0mt00085j


The world of cucurbiturils - From peculiarity to commodity
Nau WM, Scherman OA
Israel Journal of Chemistry 2011, 3, 492-494.


Plasmonic junctions with cucurbit[5]uril glue: Fabrication of precise sub-nm junctions in gold nanoparticle assemblies
Taylor RW, Lee TC, Scherman OA, Esteban R, Aizpurua J, Huang FM, Baumberg JJ, Mahajan S
2011 Conference on Lasers and Electro-Optics: Laser Science to Photonic Applications, CLEO 2011 2011, 0, -.


A supramolecular route for reversible protein-polymer conjugation
Biedermann F, Rauwald U, Zayed JM, Scherman OA
CHEM SCI 2011, 15, 279-286. DOI: 10.1039/C0SC00435A


Importance of relative humidity in the oxidative ageing of organic aerosols: case study of the ozonolysis of maleic acid aerosol
Gallimore PJ, Achakulwisut P, Pope FD, Davies JF, Spring DR, Kalberer M
ATMOS CHEM PHYS 2011, 1, 12181-12195. DOI: 10.5194/acp-11-12181-2011


Catalytic enantioselective assembly of complex molecules containing embedded quaternary stereogenic centres from simple anisidine derivatives
Leon R, Jawalekar A, Redert T, Gaunt MJ
CHEM SCI 2011, 3, 1487-1490. DOI: 10.1039/C1SC00218J


Amine directed Pd(II)-catalyzed C-H bond functionalization under ambient conditions
Haffemayer B, Gulias M, Gaunt MJ
CHEM SCI 2011, 16, 312-315. DOI: 10.1039/C0SC00367K


Self-assembly of trehalose molecules on a lysozyme surface: the broken glass hypothesis
Fedorov MV, Goodman JM, Nerukh D, Schumm S
PHYS CHEM CHEM PHYS 2011, 2, 2294-2299. DOI: 10.1039/C0CP01705A


How reliable are DFT transition structures? Comparison of GGA, hybrid-meta-GGA and meta-GGA functionals
Simon L, Goodman JM
ORG BIOMOL CHEM 2011, 16, 689-700. DOI: 10.1039/C0OB00477D


Structure-activity studies of the pelorusides: new congeners and semi-synthetic analogues
Singh AJ, Razzak M, Teesdale-Spittle P, Gaitanos TN, Wilmes A, Paterson I, Goodman JM, Miller JH, Northcote PT
ORG BIOMOL CHEM 2011, 2, 4456-4466. DOI: 10.1039/C0OB01127D


Supramolecular chemistry of monochiral naphthalenediimides
Anderson TW, Pantos GD, Sanders JKM
ORG BIOMOL CHEM 2011, 0, 7547-7553. DOI: 10.1039/C1OB06147J


Ruthenium(II) and rhodium(III) porphyrin phosphine complexes: influence of substitution pattern on structure and electronic properties
Bond AD, Sanders JKM, Stulz E
NEW J CHEM 2011, 1, 2691-2696. DOI: 10.1039/C1NJ20598F


From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries
Beeren SR, Pittelkow M, Sanders JKM
CHEM COMMUN 2011, 1, 7359-7361. DOI: 10.1039/C1CC12268A


Ferrocene-amino acid macrocycles as hydrazone-based receptors for anions
Beeren SR, Sanders JKM
CHEM SCI 2011, 3, 1560-1567. DOI: 10.1039/C1SC00168J


Dudley Williams Obituary
Sanders JKM
ANGEW CHEM INT EDIT 2011, 0, 2431-2432. DOI: 10.1002/anie.201100049


Complexes of aryl-substituted porphyrins and naphthalenediimide (NDI): investigations by synchrotron X-ray diffraction and NMR spectroscopy
Tong LH, Pengo P, Clegg W, Lowe JP, Raithby PR, Sanders JKM, Pascu SI
DALTON T 2011, 0, 10833-10842. DOI: 10.1039/C1DT10880H


A remarkably flexible and selective receptor for Ba2+ amplified from a hydrazone dynamic combinatorial library
Klein JM, Saggiomo V, Reck L, McPartlin M, Pantos GD, Luning U, Sanders JKM
CHEM COMMUN 2011, 8, 3371-3373. DOI: 10.1039/C0CC04863A


A fully self-assembled non-symmetric triad for photoinduced charge separation
Iengo E, Pantos GD, Sanders JKM, Orlandi M, Chiorboli C, Fracasso S, Scandola F
CHEM SCI 2011, 3, 676-685. DOI: 10.1039/C0SC00520G


Reactivity modulation in container molecules
Breiner B, Clegg JK, Nitschke JR
CHEM SCI 2011, 2, 51-56. DOI: 10.1039/C0SC00329H


Selective anion binding by a 'Chameleon' capsule with a dynamically reconfigurable exterior
Hristova YR, Smulders MMJ, Clegg JK, Breiner B, Nitschke JR
CHEM SCI 2011, 2, 638-641. DOI: 10.1039/C0SC00495B


Oxidation reactions in segmented and continuous flow chemical processing using an N -(tert -Butyl)phenylsulfinimidoyl chloride monolith
Lange H, Capener MJ, Jones AX, Smith CJ, Nikbin N, Baxendale IR, Ley SV
Synlett 2011, 869-873.


Oxidation Reactions in Segmented and Continuous Flow Chemical Processing Using an N-(tert-Butyl)phenylsulfinimidoyl Chloride Monolith
Lange H, Capener MJ, Jones AX, Smith CJ, Nikbin N, Baxendale IR, Ley SV
Synlett 2011, -.


Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent
Smith CJ, Smith CD, Nikbin N, Ley SV, Baxendale IR
Organic and Biomolecular Chemistry 2011, 9, 1927-1937.


An integrated flow and batch-based approach for the synthesis of O -methyl siphonazole
Baumann M, Baxendale IR, Brasholz M, Hayward JJ, Ley SV, Nikbin N
Synlett 2011, 1375-1380.


An Integrated Flow and Batch-Based Approach for the Synthesis of O-Methyl Siphonazole
Baumann M, Baxendale IR, Brasholz M, Hayward JJ, Ley SV, Nikbin N
Synlett 2011, -.


A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3- triazoles
Smith CJ, Nikbin N, Ley SV, Lange H, Baxendale IR
Organic and Biomolecular Chemistry 2011, 9, 1938-1947.


A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing
Lange H, Carter CF, Hopkin MD, Burke A, Goode JG, Baxendale IR, Ley SV
CHEM SCI 2011, 2, 765-769. DOI: 10.1039/C0SC00603C


The continuous-flow synthesis of styrenes using ethylene in a palladium-catalysed heck cross-coupling reaction
Bourne SL, Koos P, Obrien M, Martin B, Schenkel B, Baxendale IR, Ley SV
Synlett 2011, 2643-2647.


The Continuous-Flow Synthesis of Styrenes Using Ethylene in a Palladium-Catalysed Heck Cross-Coupling Reaction
Bourne SL, Koos P, O'Brien M, Martin B, Schenkel B, Baxendale IR, Ley SV
Synlett 2011, -.


Teflon AF-2400 mediated gas-liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration
Koos P, Gross U, Polyzos A, O'Brien M, Baxendale I, Ley SV
Organic and Biomolecular Chemistry 2011, 9, 6903-6908.


Syngas-mediated C-C bond formation in flow: Selective rhodium-catalysed hydroformylation of styrenes
Kasinathan S, Bourne SL, Tolstoy P, Koos P, Obrien M, Bates RW, Baxendale IR, Ley SV
Synlett 2011, 2648-2651.


Syngas-Mediated C-C Bond Formation in Flow: Selective Rhodium-Catalysed Hydroformylation of Styrenes
Kasinathan S, Bourne SL, Tolstoy P, Koos P, O'Brien M, Bates RW, Baxendale IR, Ley SV
Synlett 2011, -.


Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas-liquid contact at elevated pressure
O'Brien M, Taylor N, Polyzos A, Baxendale IR, Ley SV
CHEM SCI 2011, 2, 1250-1257. DOI: 10.1039/C1SC00055A


Piecing together the puzzle: Understanding a mild, metal free reduction method for the large scale synthesis of hydrazines
Browne DL, Baxendale IR, Ley SV
Tetrahedron 2011, 67, 10296-10303.


Synthesis of 3,4-fused cycloalkanopyrroles by 1,3-dipolar cycloaddition
Kelly JM, Leeper FJ
Tetrahedron Letters 2011, -.


Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells
Stockmann H, Neves AA, Stairs S, Ireland-Zecchini H, Brindle KM, Leeper FJ
CHEM SCI 2011, 13, 932-936. DOI: 10.1039/C0SC00631A


Solar hydrogen evolution with hydrogenases: From natural to hybrid systems
Reisner E
European Journal of Inorganic Chemistry 2011, 9, 1005-1016.


A TiO₂ nanoparticle system for sacrificial solar H₂ production prepared by rational combination of a hydrogenase with a ruthenium photosensitizer.
Reisner E, Armstrong FA
Methods Mol Biol 2011, 743, 107-117. DOI: 10.1007/978-1-61779-132-1_9


Group 13 BN dehydrocoupling reagents, similar to transition metal catalysts but with unique reactivity
Hansmann MM, Melen RL, Wright DS
CHEM SCI 2011, 2, 1554-1559. DOI: 10.1039/C1SC00154J


The Serratia LuxR family regulator CarR 39006 activates transcription independently of cognate quorum sensing signals
Poulter S, Carlton TM, Spring DR, Salmond GP
Molecular Microbiology 2011, 1120-1131.


Synthesis of Highly Substituted Symmetrical 1,3-Dienes via Organocuprate Oxidation
Aves SJ, O'Connell KM, Pike KG, Spring DR
Synlett 2011, -.


Stereoselective synthesis of disubstituted butadienes via copper-mediated coupling of alkenyl silanes
Blackwell DT, Galloway WRJD, Spring DR
Synlett 2011, 2140-2144.


Robust routes for the synthesis of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity
Hodgkinson JT, Galloway WRJD, Casoli M, Keane H, Su X, Salmond GPC, Welch M, Spring DR
Tetrahedron Letters 2011, 3291-3294.


Regioselectivity in thermal rhodium(II)-catalysed Büchner-type reactions of substituted aryl halides: Studies towards the synthesis of halide-substituted cycloheptatrienes
Wyatt EE, Galloway WRJD, Spring DR
Synlett 2011, 1449-1453.


Novel Phosphate Derivatives as Scaffolds for the Preparation of Synthetic Phosphoserine-Based Peptides Using the Fmoc/t-Bu Solid-Phase Strategy
Cilibrizzi A, Isidro-Llobet A, Mateu N, Galloway WR, Spring DR
Synlett 2011, -.


Importance of relative humidity in the oxidative ageing of organic aerosols: Case study of the ozonolysis of maleic acid aerosol
Gallimore PJ, Achakulwisut P, Pope FD, Davies J, Spring DR, Kalberer M
Atmospheric Chemistry and Physics Discussions 2011, 23169-23202.


Erratum: Structure of a blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding site (Structure (2011) 19 (1691-1700))
Bolanos-Garcia VM, Lischetti T, Matak-Vinković D, Cota E, Simpson PJ, Chirgadze DY, Spring DR, Robinson CV, Nilsson J, Blundell TL
Structure 2011, 1895-1895.


Efficient synthesis of Fmoc-protected azido amino acids
Lau YH, Spring DR
Synlett 2011, 1917-1919.


Efficient Synthesis of Fmoc-Protected Azido Amino Acids
Lau YH, Spring DR
Synlett 2011, 0, -.


Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines
Browne DL, Baxendale IR, Ley SV
Tetrahedron 2011, -.


L-proline functionalized polymers prepared by RAFT polymerization and their assemblies as supported organocatalysts
Lu A, Smart TP, Epps TH, Longbottom DA, O'Reilly RK
Macromolecules 2011, 44, 7233-7241.


Quantitative tracking of the growth of individual algal cells in microdroplet compartments
Pan J, Stephenson AL, Kazamia E, Huck WTS, Dennis JS, Smith AG, Abell C
Integrative Biology 2011, 0, 1043-1051.


Microdroplet fabrication of silver-agarose nanocomposite beads for SERS optical accumulation
Abalde-Cela S, Auguie B, Fischlechner M, Huck WTS, Alvarez-Puebla RA, Liz-Marzan LM, Abell C
SOFT MATTER 2011, 3, 1321-1325. DOI: 10.1039/C0SM00601G


Fragment screening against the thiamine pyrophosphate riboswitch thiM
Cressina E, Chen LH, Abell C, Leeper FJ, Smith AG
CHEM SCI 2011, 4, 157-165. DOI: 10.1039/C0SC00406E


Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity.
Mashalidis EH, Mukherjee T, Sledź P, Matak-Vinković D, Boshoff H, Abell C, Barry CE
PLoS One 2011, 6, e27643 -. DOI: 10.1371/journal.pone.0027643


Solid-state dynamic combinatorial chemistry: reversibility and thermodynamic product selection in covalent mechanosynthesis
Belenguer AM, Friscic T, Day GM, Sanders JKM
CHEM SCI 2011, 4, 696-700. DOI: 10.1039/C0SC00533A


ZnO based nanowires grown by chemical vapour deposition for selective hydrogenation of acetylene alcohols
Protasova LN, Rebrov EV, Choy KL, Pung SY, Engels V, Cabaj M, Wheatley AEH, Schouten JC
Catalysis Science and Technology 2011, 1, 768-777.


Ligand effects in the formation of tertiary carbanions from substituted tertiary aromatic amides
Campbell Smith A, Donnard M, Haywood J, McPartlin M, Vincent MA, Hillier IH, Clayden J, Wheatley AEH
Chemistry - A European Journal 2011, 2, 8078-8084.


Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships
Snégaroff K, Nguyen TT, Marquise N, Halauko YS, Harford PJ, Roisnel T, Matulis VE, Ivashkevich OA, Chevallier F, Wheatley AEH, Gros PC, Mongin F
Chemistry - A European Journal 2011, 1, 13284-13297.


A kinetic study of the liquid-phase hydrogenation of citral on Au/TiO 2 and Pt-Sn/TiO 2 thin films in capillary microreactors
Protasova LN, Rebrov EV, Skelton HE, Wheatley AEH, Schouten JC
Applied Catalysis A: General 2011, 12-21.


A kinetic study of the liquid-phase hydrogenation of citral on Au/TiO 2 and Pt-Sn/TiO 2 thin films in capillary microreactors
Protasova LN, Rebrov EV, Skelton HE, Wheatley AEH, Schouten JC
Applied Catalysis A: General 2011, 0, -.


A hydrogen bonded cocrystal with an unusual interweaving between the adjacent triple-helices
Delori A, Jones W
CRYSTENGCOMM 2011, 0, 6315-6318. DOI: 10.1039/C1CE05534H


Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space.
van der Horst E, Peironcely JE, van Westen GJ, van den Hoven OO, Galloway WR, Spring DR, Wegner JK, van Vlijmen HW, Ijzerman AP, Overington JP, Bender A
Curr Top Med Chem 2011, 11, 1964-1977.