Department of Chemistry

Peter J Bond Publications (2012)


Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.
Kirchmair J, Williamson MJ, Tyzack JD, Tan L, Bond PJ, Bender A, Glen RC
J Chem Inf Model, 2012, 3, 617-648. DOI: 10.1021/ci200542m


The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule.
Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, Silverman RH, Neubert TA, Baxendale IR, Ron D, Harding HP
Proc Natl Acad Sci U S A, 2012, 15, E869-E878. DOI: 10.1073/pnas.1115623109


The Molecular Basis for Lipid Recognition and Signaling in the Toll-Like Receptor Complex and a Family of Lipid-Binding Proteins
Paramo T, Higson S, Piggot TJ, Bond PJ
BIOPHYSICAL JOURNAL, 2012, 3, 664A-664A.


Insights into Membrane Fusion from Molecular Dynamics Simulations of SNARE Proteins
Tek A, Bond PJ, Sansom MSP, Baaden M
BIOPHYSICAL JOURNAL, 2012, 3, 499A-499A.


Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1.
Beale TM, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM
Bioorg Med Chem, 2012, 5, 1749-1759. DOI: 10.1016/j.bmc.2012.01.010


Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1
Beale TM, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM
Bioorganic and Medicinal Chemistry, 2012, 5, 1749-1759.


A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles
Beale TM, Allwood DM, Bender A, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM, Shearman JW, Temple J, Unger J, Watts CA, Xian J
ACS Medicinal Chemistry Letters, 2012, 3, 177-181.


Minor pseudopilin self-assembly primes type II secretion pseudopilus elongation
Cisneros DA, Bond PJ, Pugsley AP, Campos M, Francetic O
EMBO Journal, 2012, 4, 1041-1053.


Computational prediction of metabolism: Sites, products, SAR, P450 enzyme dynamics, and mechanisms
Kirchmair J, Williamson MJ, Tyzack JD, Tan L, Bond PJ, Bender A, Glen RC
Journal of Chemical Information and Modeling, 2012, 3, 617-648.