Department of Chemistry

Shankar Balasubramanian FRS Publications (2012)


An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes.
Nikan M, Di Antonio M, Abecassis K, McLuckie K, Balasubramanian S
Angew Chem Int Ed Engl, 2013, 5, 1428-1431. DOI: 10.1002/anie.201207075


An RNA hairpin to G-quadruplex conformational transition.
Bugaut A, Murat P, Balasubramanian S
J Am Chem Soc, 2012, 49, 19953-19956. DOI: 10.1021/ja308665g


The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids.
Zhang AY, Balasubramanian S
J Am Chem Soc, 2012, 46, 19297-19308. DOI: 10.1021/ja309851t


Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.
Di Antonio M, Biffi G, Mariani A, Raiber EA, Rodriguez R, Balasubramanian S
Angew Chem Int Ed Engl, 2012, 44, 11073-11078. DOI: 10.1002/anie.201206281


Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells.
Müller S, Sanders DA, Di Antonio M, Matsis S, Riou JF, Rodriguez R, Balasubramanian S
Org Biomol Chem, 2012, 32, 6537-6546. DOI: 10.1039/C2OB25830G


Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.
Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR, Murat P, Oxley D, Booth MJ, Reik W, Balasubramanian S
Genome Biol, 2012, 8, R69-. DOI: 10.1186/gb-2012-13-8-r69


An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2.
Biffi G, Tannahill D, Balasubramanian S
J Am Chem Soc, 2012, 29, 11974-11976. DOI: 10.1021/ja305734x


Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S
Science, 2012, 6083, 934-937. DOI: 10.1126/science.1220671


Comparative structural effects of HIV-1 Gag and nucleocapsid proteins in binding to and unwinding of the viral RNA packaging signal.
Bell NM, Kenyon JC, Balasubramanian S, Lever AM
Biochemistry, 2012, 15, 3162-3169. DOI: 10.1021/bi2017969


5'-UTR RNA G-quadruplexes: translation regulation and targeting.
Bugaut A, Balasubramanian S
Nucleic Acids Res, 2012-06, 11, 4727-4741. DOI: 10.1093/nar/gks068


Experimental approaches to identify cellular G-quadruplex structures and functions.
Di Antonio M, Rodriguez R, Balasubramanian S
Methods, 2012-05, 1, 84-92. DOI: 10.1016/j.ymeth.2012.01.008


Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy.
Mela I, Kranaster R, Henderson RM, Balasubramanian S, Edwardson JM
Biochemistry, 2012, 2, 578-585. DOI: 10.1021/bi201600g


Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP
Nature Chemical Biology, 2012, -.