Department of Chemistry

Shankar Balasubramanian Publications (2012)


An RNA hairpin to g-quadruplex conformational transition.
Bugaut A, Murat P, Balasubramanian S
J Am Chem Soc 2012, 134, 19953-19956. DOI: 10.1021/ja308665g


The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids.
Zhang AY, Balasubramanian S
J Am Chem Soc 2012, 134, 19297-19308. DOI: 10.1021/ja309851t


Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.
Di Antonio M, Biffi G, Mariani A, Raiber EA, Rodriguez R, Balasubramanian S
Angew Chem Int Ed Engl 2012, 51, 11073-11078. DOI: 10.1002/anie.201206281


Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells.
Müller S, Sanders DA, Di Antonio M, Matsis S, Riou JF, Rodriguez R, Balasubramanian S
Org Biomol Chem 2012, 6537-6546. DOI: 10.1039/C2OB25830G


Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.
Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR, Murat P, Oxley D, Booth MJ, Reik W, Balasubramanian S
Genome Biol 2012, 13, R69 -. DOI: 10.1186/gb-2012-13-8-r69


An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2.
Biffi G, Tannahill D, Balasubramanian S
J Am Chem Soc 2012, 11974-11976. DOI: 10.1021/ja305734x


5'-UTR RNA G-quadruplexes: translation regulation and targeting.
Bugaut A, Balasubramanian S
2012, 40, 4727-4741. DOI: 10.1093/nar/gks068


Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S
Science 2012, 336, 934-937. DOI: 10.1126/science.1220671


Comparative Structural Effects of HIV-1 Gag and Nucleocapsid Proteins in Binding to and Unwinding of the Viral RNA Packaging Signal.
Bell NM, Kenyon JC, Balasubramanian S, Lever AM
Biochemistry 2012, 51, 3162-3169. DOI: 10.1021/bi2017969


Experimental approaches to identify cellular G-quadruplex structures and functions.
Antonio MD, Rodriguez R, Balasubramanian S
Methods 2012, -. DOI: 10.1016/j.ymeth.2012.01.008


FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.
Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE
Nucleic Acids Res 2012, 40, 1485-1498. DOI: 10.1093/nar/gkr868


A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro.
Raiber EA, Kranaster R, Lam E, Nikan M, Balasubramanian S
Nucleic Acids Res 2012, 40, 1499-1508. DOI: 10.1093/nar/gkr882


Demonstration of ligand decoration, and ligand-induced perturbation, of g-quadruplexes in a plasmid using atomic force microscopy.
Mela I, Kranaster R, Henderson RM, Balasubramanian S, Edwardson JM
Biochemistry 2012, 51, 578-585. DOI: 10.1021/bi201600g


Synthesis of Bis-indole Carboxamides as G-Quadruplex Stabilizing and Inducing Ligands.
Dash J, Nath Das R, Hegde N, Pantoş GD, Shirude PS, Balasubramanian S
Chemistry 2012, 18, 554-564. DOI: 10.1002/chem.201102556


Quantitative Sequencing of 5-Methyl-cytosine and 5-Hydroxymethylcytosine at Single-Base Resolution
Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S
Science 2012, 1-4.


Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP
Nature Chemical Biology 2012, -.


Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP
Nat Chem Biol 2012, 8, 301-310. DOI: 10.1038/nchembio.780


Experimental approaches to identify cellular G-quadruplex structures and functions
Di Antonio M, Rodriguez R, Balasubramanian S
Methods 2012, 84-92.