the goodman group this list is a product of research in the Goodman Group;
it is not the official department of chemistry list of
academics or academic publications
university of cambridge  


List papers in: all subjects | Biological | Materials | Physical | Synthesis | Theory, Modelling and Informatics
David R Spring Publications


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The Application of Ligand-Mapping Molecular Dynamics Simulations to the Rational Design of Peptidic Modulators of Protein–Protein Interactions
Yaw Sing Tan, David R Spring, Chris Abell, and Chandra S Verma
Journal_of_Chemical_Theory_and_Computation DOI: 10.1021/ct5010577


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Enantioselective Synthesis of Chromanones via a Peptidic Phosphane Catalyzed Rauhut–Currier Reaction
Robert J H Scanes, Oleg Grossmann, André Grossmann, and David R Spring
Organic_Letters DOI: 10.1021/acs.orglett.5b00971


, 2015-10-05, -


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A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds
Albert Isidro-Llobet, Kathy Hadje Georgiou, Warren R J D Galloway, Elisa Giacomini, Mette R Hansen, Gabriela Mendez-Abt, Yaw Sing Tan, Laura Carro, Hannah F Sore, David R Spring
Organic_and_Biomolecular_Chemistry DOI: 10.1039/C5OB00371G


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Linear Aliphatic Dialkynes as Alternative Linkers for Double-Click Stapling of p53-Derived Peptides
Yu Heng Lau, Dr Peterson de Andrade, Dr Grahame J McKenzie, Prof Ashok R Venkitaraman and Prof David R Spring
ChemBioChem DOI: 10.1002/cbic.201402374


, 2015-08-03, -


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Diversity-Oriented Synthesis of Drug-Like Macrocyclic Scaffolds Using an Orthogonal Organo- and Metal Catalysis Strategy
Dr André Grossmann, Sean Bartlett, Matej Janecek, Dr James T Hodgkinson and Prof David R Spring
Angewandte_Chemie_International_Edition DOI: 10.1002/anie.201406865


, 2015-09-16, -


Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck-Suzuki reaction
Esther Alza, Luca Laraia, Brett M Ibbeson, Suil Collins, Warren R J D Galloway, Jamie E Stokes, Ashok R Venkitaraman, David R Spring
Chemical_Science DOI: 10.1039/C4SC02547D


Peptide stapling techniques based on different macrocyclisation chemistries
Yu Heng Lau, Peterson de Andrade, Yuteng Wu, David R Spring
Chemical_Society_Reviews DOI: 10.1039/C4CS00246F


, 2015-07-30, -


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Concise Synthesis of Substituted Quinolizin-4-ones by Ring-Closing Metathesis
Thomas A Alanine, Warren R J D Galloway, Thomas M McGuire and David R Spring
European_Journal_of_Organic_Chemistry DOI: 10.1002/ejoc.201402648


, 2015-03-09, -


Arene C-H functionalisation using a removable/modifiable or a traceless directing group strategy
Fengzhi Zhang, David R Spring
Chemical_Society_Reviews DOI: 10.1039/C4CS00137K


, 2015-05-19, -


The Use of Chlorobenzene as a Probe Molecule in Molecular Dynamics Simulations
Yaw Sing Tan, David R Spring, Chris Abell, and Chandra Verma
Journal_of_Chemical_Information_and_Modeling DOI: 10.1021/ci500215x


, 2015-07-21, -


Investigating peptide sequence variations for 'double-click' stapled p53 peptides
Yu Heng Lau, Peterson de Andrade, Niklas Skold, Grahame J McKenzie, Ashok R Venkitaraman, Chandra Verma, David P Lane, David R Spring
Organic_and_Biomolecular_Chemistry DOI: 10.1039/C4OB00742E


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Functionalised staple linkages for modulating the cellular activity of stapled peptides
Yu Heng Lau, Peterson de Andrade, Soo-Tng Quah, Maxim Rossmann, Luca Laraia, Niklas Skold, Tze Jing Sum, Pamela J E Rowling, Thomas L Joseph, Chandra Verma, Marko Hyvonen, Laura S Itzhaki, Ashok R Venkitaraman, Christopher J Brown, David P Lane, David R Spring
Chemical_Science DOI: 10.1039/C4SC00045E


Diversity-oriented synthesis as a tool for identifying new modulators of mitosis
Brett M Ibbeson, Luca Laraia, Esther Alza, Cornelius J O' Connor, Yaw Sing Tan, Huw M.L Davies, Grahame McKenzie, Ashok R Venkitaraman, David R Spring
Nature_Communications DOI: 10.1038/ncomms4155


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