Department of Chemistry

David Klenerman Publications (recent)

Imaging the cell surface and its organization down to the level of single molecules.
Klenerman D, Shevchuk A, Novak P, Korchev YE, Davis SJ
Philos Trans R Soc Lond B Biol Sci 2013, 368, 20120027 -. DOI: 10.1098/rstb.2012.0027

Single Molecule Characterization of the Interactions between Amyloid-β Peptides and the Membranes of Hippocampal Cells.
Narayan P, Ganzinger KA, McColl J, Weimann L, Meehan S, Qamar S, Carver JA, Wilson MR, St George-Hyslop P, Dobson CM, Klenerman D
J Am Chem Soc 2013, 135, 1491-1498. DOI: 10.1021/ja3103567

Pipette-surface interaction: current enhancement and intrinsic force.
Clarke RW, Zhukov A, Richards O, Johnson N, Ostanin V, Klenerman D
J Am Chem Soc 2013, 135, 322-329. DOI: 10.1021/ja3094586

Amyloid-β Oligomers are Sequestered by both Intracellular and Extracellular Chaperones.
Narayan P, Meehan S, Carver JA, Wilson MR, Dobson CM, Klenerman D
Biochemistry 2012, 51, 9270-9276. DOI: 10.1021/bi301277k

A hybrid scanning mode for fast scanning ion conductance microscopy (SICM) imaging.
Zhukov A, Richards O, Ostanin V, Korchev Y, Klenerman D
Ultramicroscopy 2012, 121, 1-7. DOI: 10.1016/j.ultramic.2012.06.015

Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy.
Takahashi Y, Shevchuk AI, Novak P, Babakinejad B, Macpherson J, Unwin PR, Shiku H, Gorelik J, Klenerman D, Korchev YE, Matsue T
Proc Natl Acad Sci U S A 2012, 109, 11540-11545. DOI: 10.1073/pnas.1203570109

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.
Lando D, Endesfelder U, Berger H, Subramanian L, Dunne PD, McColl J, Klenerman D, Carr AM, Sauer M, Allshire RC, Heilemann M, Laue ED
Open Biol 2012, 2, 120078 -. DOI: 10.1098/rsob.120078

Hydrodynamic trapping of molecules in lipid bilayers.
Jönsson P, McColl J, Clarke RW, Ostanin VP, Jönsson B, Klenerman D
Proc Natl Acad Sci U S A 2012, 109, 10328-10333. DOI: 10.1073/pnas.1202858109

Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D
Cell 2012, 149, 1048-1059. DOI: 10.1016/j.cell.2012.03.037

An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy.
Shevchuk AI, Novak P, Taylor M, Diakonov IA, Ziyadeh-Isleem A, Bitoun M, Guicheney P, Lab MJ, Gorelik J, Merrifield CJ, Klenerman D, Korchev YE
J Cell Biol 2012, 197, 499-508. DOI: 10.1083/jcb.201109130