Department of Chemistry

Synthesis Publications (recent)

Continuous Flow Chemistry: A Discovery Tool for New Chemical Reactivity Patterns
Steven V Ley, Jan Benedikt Metternich, Nikzad Nikbin, Jan Hartwig, Andreas Kirschning
Organic_and_Biomolecular_Chemistry DOI: 10.1039/C4OB00662C

A Study of the Optical Properties of Metal-doped Polyoxotitanium Cages and the Relationship to Metal-doped Titania
YaoKang Lv, Jun Cheng, Peter Matthews, Juan P Holgado, Janina Willkomm, Michal Leskes, Alexander Steiner, Dieter Fenske, Timothy C King, Paul Wood, Lihua Gan, Richard M Lambert, Dominic S Wright
Dalton_Transactions DOI: 10.1039/C4DT00555D

Accelerating Spirocyclic Polyketide Synthesis using Flow Chemistry
Dr Sean Newton, Dr Catherine F Carter, Dr Colin M Pearson, Leandrode C Alves, Dr Heiko Lange, Dr Praew Thansandote and Prof Steven V Ley
Angewandte_Chemie_International_Edition DOI: 10.1002/anie.201402056

Reprogramming the Mechanism of Action of Chlorambucil by Coupling to a G-Quadruplex Ligand
Marco Di Antonio, Keith I E McLuckie, and Shankar Balasubramanian
Journal_of_the_American_Chemical_Society DOI: 10.1021/ja5014344

Supramolecular Polymerization Promoted and Controlled through Self-sorting
Zehuan Huang, Liulin Yang, Yiliu Liu, Prof Zhiqiang Wang, Dr Oren A Scherman and Prof Xi Zhang
Angewandte_Chemie_International_Edition DOI: 10.1002/anie.201402817

Selective Encapsulation and Sequential Release of Guests Within a Self-Sorting Mixture of Three Tetrahedral Cages
Dr Azucena Jiménez, Dr Rana A Bilbeisi, Dr Tanya K Ronson, Dr Salvatore Zarra, Craig Woodhead and Dr Jonathan R Nitschke
Angewandte_Chemie_International_Edition DOI: 10.1002/anie.201400541

Protein film photoelectrochemistry of the water oxidation enzyme photosystem II
Masaru Kato, Jenny Z Zhang, Nicholas Paul, Erwin Reisner
Chemical_Society_Reviews DOI: 10.1039/C4CS00031E

G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation.
Murat P, Zhong J, Lekieffre L, Cowieson NP, Clancy JL, Preiss T, Balasubramanian S, Khanna R, Tellam J
Nat Chem Biol, 2014, -. DOI: 10.1038/nchembio.1479

Functionalised staple linkages for modulating the cellular activity of stapled peptides
Yu Heng Lau, Peterson de Andrade, Soo-Tng Quah, Maxim Rossmann, Luca Laraia, Niklas Skold, Tze Jing Sum, Pamela J E Rowling, Thomas L Joseph, Chandra Verma, Marko Hyvonen, Laura S Itzhaki, Ashok R Venkitaraman, Christopher J Brown, David P Lane, David R Spring
Chemical_Science DOI: 10.1039/C4SC00045E

Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography
Lucie Guetzoyan, Richard Ingham, Nikzad Nikbin, Julien Rossignol, Michael Wolling, Mark Baumert, Nicola A Burgess-Brown, Claire M Strain-Damerell, Leela Shrestha, Paul Brennan, Oleg Fedorov, Stefan Knapp, Steven V Ley
MedChemComm DOI: 10.1039/C4MD00007B