Known and Suspected Carcinogens

The following chemicals are known or suspected carcinogens. This list has been compiled from a number of sources (in particular, we are grateful for data from the excellent Cornell carcinogen database), but it is by no means comprehensive.

Therefore, the absence of a chemical from this list does not mean that it cannot have carcinogenic properties. Neither does the presence of a chemical in the list indicate that it is a proven carcinogen.

However, users should treat the following materials with the caution due to suspected carcinogens, and gather as much safety data as possible before starting work. Restrictions apply to the use of some of these chemicals in the U.K. We have done our best

This is the list from the Oxford web site http://physchem.ox.ac.uk/MSDS/carcinogens.html with some local additions. Updated March 23, 1998 PG


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A

A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
Acetaldehyde
Acetamide
Acetochlor
2-Acetylaminofluorene
Acifluorfen
Acrylamide
Acrylonitrile
Actinomycin D
Adriamycin (Doxorubicin hydrochloride)
AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide
Aflatoxins
Agaritine
Alachlor
Aldrin
Allyl chloride
Allyl isothiocyanae
Allyl isovalerate
Aluminium products
2-Aminoanthraquinone
p-Aminoazobenzene
o-Aminoazotoluene [solvent yellow 3]
4-Aminobiphenyl (4-aminodiphenyl)
3-Amino-9-ethylcarbazole hydrochloride
1-Amino-2-methylanthraquinone
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole amino-5-nitrothiazole, 2-
Amitrole
Analgesic mixtures containing phenacetin
Androgenic (anabolic) steroids
Aniline
ortho-Anisidine
ortho-Anisidine hydrochloride anthanthrene
Antimony oxide (antimony trioxide)
Aramite
Arsenic (inorganic arsenic compounds)
Asbestos
Auramine
Azaserine
Azathioprine
Azacitidine
Azobenzene
Azathioprine


B

Benz[a]anthracene
Benzene
Benzene-d6
Benzidine [and its salts]
Benzidine-based dyes
Benzo[b]fluoranthene
Benzo[j]fluoranthene
Benzo[k]fluoranthene
Benzofuran
Benzo[a]pyrene
Benzotrichloride
Benzyl chloride
Benzyl violet 4B
Beryllium and beryllium compounds
Bis(2-chloroethyl)ether
N,N-Bis(2-chloroethyl)-2- naphthylamine (Chlornapazine)
Bischloroethyl nitrosourea (BCNU) (Carmustine)
Bis(chloromethyl)ether and technical-grade chloromethyl methyl ether
Bitumens, extracts of steam-refined and air refined
Bleomycins
Bracken fern
Bromodichloromethane
Bromoform
1,3-Butadiene
1,4-Butanediol dimethanesulfonate (Busulfan, myleran)
Butylated hydroxyanisole (BHA)
beta-Butyrolactone


C

Cadmium and cadmium compounds
Caffeic acid
Captafol
Captan
Carbazole
Carbon tetrachloride
Carbon-black extracts
Carrageenan, degraded
Ceramic fibers (airborne particles of respirable size)
Chlorambucil
Chloramphenicol
chlorbenzilat
Chlordane
Chlordecone (Kepone)
Chlordimeform
Chlorendic acid
Chlorinated Parrafins
alpha-Chlorinated toluenes
p-Chloroaniline
Cchlormadinone aceate
Chlornaphazine[n,n-bis(2-chloroethyl)-2-naphthylamine]
Chlorodibromomethane
Chloroethane (ethyl chloride)
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (Lomustine)
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU)
Chloroform
Chloroform-d
Chloromethyl methyl ether
3-Chloro-2-methylpropene
4-Chloro-ortho-phenylenediamine
p-Chloro-o-toluidine
Chlorophenols
Chlorophenoxy herbicides
Cloroprene
Chlorothalonil
Chlorozotocin
Chromim
Chromium (hexavalent compounds)
Chrysene
C. I. Acid Red 114
C. I. Basic Red 9 monohydrochloride
Ciclosporin (Cyclosporin A; Cyclosporine)
Cinnamyl anthranilate
Cisplatin
Citrus Red No. 2
Clofibrate
Coal gasification
Coal-tar pitches
Coal-tars
Cobalt metal powder
Cobalt [II] oxide
Conjugated estrogens
Creosotes
para-Cresidine
Cupferron
Cycasin
Cyclamates
Cyclophosphamide (anhydrous)
Cyclophosphamide (hydrated)


D

D&C Orange No. 17
D&C Red No. 8
D&C Red No. 9
D&C Red No. 19
Dacarbazine
Daminozide
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)
dapsone
Daunomycin
DCM
DDD (Dichlorodiphenyldichloroethane)
DDE (Dichlorodiphenyldichloroethylene)
DDT (Dichlorodiphenyltrichloroethane)
DDVP (Dichlorvos)
decabromodiphyenyl oxide
N,N'-Diacetylbenzidine
2,4-Diaminoanisole
2,4-Diaminoanisole sulfate
4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline)
2,4-Diaminotoluene
Diaminotoluene (mixed)
Dibenz[a,h]acridine
Dibenz[a,j]acridine
Dibenz[a,h]anthracene
7H-Dibenzo[c,g]carbazole
Dibenzo[a,e]pyrene
Dibenzo[a,h]pyrene
Dibenzo[a,i]pyrene
Dibenzo[a,l]pyrene
1,2-Dibromo-3-chloropropane (DBCP)
1,2-Dibromoethane
2,3-Dibromo-1-propanol
p-Dichlorobenzene
3,3'-Dichlorobenzidine
3,3'-Dichlorobenzidine dihydrochloride
1,4-Dichloro-2-butene
3,3'-Dichloro-4,4'-diaminodiphenyl ether
1,1-Dichloroethane
1,2-Dichloroethane
Dichloromethane (Methylene chloride)
1,2-Dichloropropane
1,3-Dichloropropene
Dieldrin
Dienestrol
Diepoxybutane
Di(2-ethylhexyl)phthalate
1,2-Diethylhydrazine
Diethyl sulfate
DES, Diethylstilbestrol
Diglycidyl resorcinol ether (DGRE)
Dihydrosafrole
Diisopropyl sulfate
3,3'-Dimethoxybenzidine (ortho-Dianisidine)
3,3'-Dimethoxybenzidine dihydrochloride (ortho-dianisidine dihydrochloride)
para-Dimethylaminoazobenzene
4-Dimethylaminoazobenzene
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-
oxadiazole
7,12-Dimethylbenz(a)anthracene
3,3'-Dimethylbenzidine (ortho-Tolidine)
3,3'-Dimethylbenzidine dihydrochloride
Dimethylcarbamoyl chloride
1,1-Dimethylhydrazine (UDMH)
1,2-Dimethylhydrazine
Dimethyl sulfate
Dimethylvinyl Chloride
1,6-Dinitropyrene
1,8-Dinitropyrene
2,4-Dinitrotoluene
2,6-Dinitrotoluene
1,4-Dioxane
Diphenylhydantoin (Phenytoin)
Diphenylhydantoin (Phenytoin), sodium salt
Direct Black 38
Direct Blue 6
Direct Brown 95
Disperse Blue 1


E

Epichlorohydrin
Erionite
Estradiol 17B
Estrogens (not conjugated)

   * Estradiol-17
   * Estrone
   * Ethinylestradiol
   * Mestranol

Estrone
Ethinylestradiol
Ethyl acrylate
Ethyl methanesulfonate
Ethyl-4,4'-dichlorobenzilate
Ethylene dibromide
Ethylene dichloride (1,2-Dichloroethane)
N-Ethyl-N-nitrosourea
Ethylene oxide
Ethylene thiourea
Ethyleneimine


F

Folpet
Formaldehyde (gas or aqueous solution)
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl) thiazole
Furan
Furazolidone
Furmecyclox
Fusarin C


G

Glasswool fibers (airborne particles of respirable size)
Glu-P-1 (2-Amino-6-methyldipyrido[1,2- a:3', 2'-d]imidazole)
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
Glycidaldehyde
Glycidol
Griseofulvin
Gyromitrin (Acetaldehyde methylformylhydrazone)


H

HC Blue 1
Heptachlor
Heptachlor epoxide
Hexachlorobenzene
Hexachlorocyclohexanes
Hexachlorodibenzodioxin
Hexachloroethane
Hexamethylphosphoramide
Hydrazine
Hydrazine sulfate
Hydrazobenzene (1,2-Diphenylhydrazine)


I

Indeno [1,2,3-cd]pyrene
Iodoform
IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)
Iron dextran complex
Isosafrole


J


K

Kepone (Chlordecone)


L

Lactofen
Lasiocarpine
Lead
Lead acetate
Lead phosphate
Lindane and other hexachlorocyclohexane isomers


M

Mancozeb
Maneb
Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2, 3-b]indole)
Medroxyprogesterone acetate
MeIQ(2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
MeIQx(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
Melphalan
Merphalan
Mestranol
2-Methylaziridine (Propyleneimine)
Methylazoxymethanol
Methylazoxymethanol acetate
3-Methylcholanthrene
5-Methylchrysene
4,4'-Methylene bis(2-chloroaniline) (MOCA)
4,4'-Methylene bis(N,N-dimethyl)benzenamine
4,4'-Methylene bis(2-methylaniline)
4,4'-Methylenedianiline
4,4'-Methylenedianiline dihydrochloride
Methylhydrazine and its salts
Methyl chloromethyl ether
Methyl-CCNU
Methyl iodide
Methyl methanesulfonate
2-Methyl-1-nitroanthraquinone
N-Methyl-N'-nitro-N-nitrosoguanidine (MNNG)
N-Methyl-N-nitrosourea
N-Methylolacrylamide
Methylthiouracil
Metiram
Metronidazole
Michler's ketone
Mineral Oils, untreated and mildly treated
Mirex
Mitomycin C
MOPP
Monocrotaline
5-(Morpholinomethyl)-3-[(5-nitro-fufurylidene)-amino]-2-oxazolidinone
Mustard gas


N

Nafenopin
1-Naphthylamine
2-Naphthylamine
3-Naphthylamine
Nickel and certain nickel compounds
Nickel carbonyl
Nickel subsulfide
Niridazole
Nitrilotriacetic acid
Nitrilotriacetic acid, trisodium salt monohydrate
5-Nitroacenaphthene
5-Nitro-o-anisidine
o-Nitroanisole
4-Nitrobiphenyl
6-Nitrochrysene
Nitrofen
2-Nitrofluorene
Nitrofurazone
1-[(5-Nitrofurfurylidene)amino]-2-imidazollidinone
1-[(5-Nitrofurfurylidene)-N-[4-(5-Nitro-2-furyl)-2 thiazolyl]acetamide
Nitrogen mustard (Mechlorethamine)
Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride)
Nitrogen mustard N-oxide
Nitrogen mustard N-oxide hydrochloride
2-Nitropropane
4-Nitropyrene
N-Nitrosodi-n-butylamine
N-Nitrosodiethanolamine
N-Nitrosodiethylamine
N-Nitrosodimethylamine
p-Nitrosodiphenylamine
N-Nitrosodiphenylamine
N-Nitrosodi-n-propylamine
N-Nitroso-N-ethylurea
3-(N-Nitrosomethylamino)propionitrile
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)
N-Nitrosomethylethylamine
N-Nitroso-N-methylurea
N-Nitroso-N-methylurethane
N-Nitrosomethylvinylamine
N-Nitrosomorpholine
N-Nitrosonornicotine
N-Nitrosopiperidine
N-Nitrosopyrrolidine
N-Nitrososarcosine
Norethisterone (Norethindrone)


O

Ochratoxin A
Oestrogen, nonstreoidal
Oestrogen, steroidal
Oil Orange SS
4,4'-Oxydianiline
Oxadiazon
Oxymetholone
Oxazepam


P

Panfuran S
Pentachlorophenol
Phenacetin
Phenazopyridine hydrochloride
Phenesterin
Phenobarbital
Phenoxybenzamine
Phenoxybenzamine hydrochloride
Phenyl glycidyl ether
Phenylhydrazine and its salts
o-Phenylphenate, sodium
Phenytoin
PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine)
Polybrominated biphenyls
Polychlorinated biphenyls
Polychlorinated biphenyls (containing 60 or more percent chlorine by
molecular weight)
Polychlorinated dibenzo-p-dioxins
Polychlorinated dibenzofurans
Polycyclic aromatic hydrocarbons
Polygeenan
Ponceau MX
Ponceau 3R
Potassium bromate
Procarbazine
Procarbazine hydrochloride
Procymidone
Progesterone
Progestins
1,3-Propane sultone
Progargite
beta-Propiolactone
Propylene oxide
Propylthiouracil


Q


R

Radionuclides
Radon
Reserpine
Residual (heavy) fuel oils


S

Saccharin
Saccharin, sodium
Safrole
Selenium sulfide
Shale-oils
Silica, crystalline (airborne particles of respirable size)
Sodium dichromate
Sodium hexafluoroarsenate(V)
Sodium ortho-phenylphenate
Sterigmatocystin
Streptozotocin
Styrene
Styrene oxide
Sulfallate
Sulphur trioxide
Sulphur trioxide N,N-dimethylformamide complex


T

Talc containing asbestiform fibers
Terrazole
Testosterone and its esters
2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD)
1,1,2,2-Tetrachloroethane
Tetrachloroethylene (Perchloroethylene)
p-a,a,a-Tetrachlorotoluene
3,3',5,5'-tetramethylbenzidine
Tetranitromethane
Thioacetamide
4,4'-Thiodianiline
Thiourea
Thorium dioxide
Tobacco, oral use of smokeless products
Tobacco smoke
Toluene diisocyanate
p-toluenesulphonic acid
ortho-Toluidine
ortho-Toluidine hydrochloride
para-Toluidine
Toxaphene (Polychorinated camphenes)
Treosulfan (Tresoluphan)
Trichlormethine (Trimustine hydrochloride)
2,4,6-Trichlorophenol
1,2,3-Trichloropropane
Triphenyltin hydroxide
Trichloroethylene
Tris(aziridinyl)-para-benzoquinone (Triaziquone)
Tris(1-aziridinyl)phosphine sulfide (Thiotepa)
Tris(2-chloroethyl) phosphate
Tris(2,3-dibromopropyl)phosphate
Trp-P-1 (Tryptophan-P-1) (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
Trp-P-2 (Tryptophan-P-2) (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
Trypan blue


U

Uracil mustard
Urethane (Ethyl carbamate)


V

Vinyl bromide
Vinyl chloride
4-Vinyl-1-cyclohexene diepoxide (Vinyl cyclohexene dioxide)
Vinyl trichloride (1,1,2-Trichloroethane)


Y


X

2,6-Xylidine (2,6-Dimethylaniline)


Y


Z

Zineb

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