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   Dolabriferol

In 1996, we predicted that it should be possible to make dolabriferol by this pathway, after a computational analysis of the many competing processes that could result from the rearrangement (Org. Lett. 2005, 7, 3541-3544 and J. Chem. Inf. Model. 2006, 46, 606-614). We now report the total synthesis of dolabriferol, based on this strategy.
In Silico Inspired Total Synthesis of (-)-Dolabriferol
R. H. Currie and J. M. Goodman Angew. Chem. 2012 Early View
DOI: 10.1002/anie.201109080



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department of chemistry University of Cambridge