Department of Chemistry

David Klenerman Publications (2012)


Amyloid-β Oligomers are Sequestered by both Intracellular and Extracellular Chaperones.
Narayan P, Meehan S, Carver JA, Wilson MR, Dobson CM, Klenerman D
Biochemistry 2012, 51, 9270-9276. DOI: 10.1021/bi301277k


A hybrid scanning mode for fast scanning ion conductance microscopy (SICM) imaging.
Zhukov A, Richards O, Ostanin V, Korchev Y, Klenerman D
Ultramicroscopy 2012, 121, 1-7. DOI: 10.1016/j.ultramic.2012.06.015


Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy.
Takahashi Y, Shevchuk AI, Novak P, Babakinejad B, Macpherson J, Unwin PR, Shiku H, Gorelik J, Klenerman D, Korchev YE, Matsue T
Proc Natl Acad Sci U S A 2012, 109, 11540-11545. DOI: 10.1073/pnas.1203570109


Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.
Lando D, Endesfelder U, Berger H, Subramanian L, Dunne PD, McColl J, Klenerman D, Carr AM, Sauer M, Allshire RC, Heilemann M, Laue ED
Open Biol 2012, 2, 120078 -. DOI: 10.1098/rsob.120078


Hydrodynamic trapping of molecules in lipid bilayers.
Jönsson P, McColl J, Clarke RW, Ostanin VP, Jönsson B, Klenerman D
Proc Natl Acad Sci U S A 2012, 109, 10328-10333. DOI: 10.1073/pnas.1202858109


Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D
Cell 2012, 149, 1048-1059. DOI: 10.1016/j.cell.2012.03.037


An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy.
Shevchuk AI, Novak P, Taylor M, Diakonov IA, Ziyadeh-Isleem A, Bitoun M, Guicheney P, Lab MJ, Gorelik J, Merrifield CJ, Klenerman D, Korchev YE
J Cell Biol 2012, 197, 499-508. DOI: 10.1083/jcb.201109130


Single Molecule Fluorescence under Conditions of Fast Flow.
Horrocks MH, Li H, Shim JU, Ranasinghe RT, Clarke RW, Huck WT, Abell C, Klenerman D
Anal Chem 2012, 84, 179-185. DOI: 10.1021/ac202313d


Single Molecule Fluorescence under Conditions of Fast Flow.
Horrocks MH, Li H, Shim JU, Ranasinghe RT, Clarke RW, Huck WT, Abell C, Klenerman D
Anal Chem 2012, 84, 179-185. DOI: 10.1021/ac202313d


The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide.
Narayan P, Orte A, Clarke RW, Bolognesi B, Hook S, Ganzinger KA, Meehan S, Wilson MR, Dobson CM, Klenerman D
Nat Struct Mol Biol 2012, 19, 79-83. DOI: 10.1038/nsmb.2191


Ubiquitin chain conformation regulates recognition and activity of interacting proteins
Ye Y, Blaser G, Horrocks MH, Ruedas-Rama MJ, Ibrahim S, Zhukov AA, Orte A, Klenerman D, Jackson SE, Komander D
Nature 2012, 492, 266-270.


The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β 1-40 peptide
Narayan P, Orte A, Clarke RW, Bolognesi B, Hook S, Ganzinger KA, Meehan S, Wilson MR, Dobson CM, Klenerman D
Nature Structural and Molecular Biology 2012, 19, 79-84.


Fluorophore conjugates for single molecule work
Ranasinghe RT, Klenerman D
RSC Biomolecular Sciences 2012, 34-74.