Department of Chemistry

Jane Clarke Publications (2012)


Take home lessons from studies of related proteins.
Nickson AA, Wensley BG, Clarke J
Curr Opin Struct Biol, 2013-02, 1, 66-74. DOI: 10.1016/j.sbi.2012.11.009


Understanding pathogenic single-nucleotide polymorphisms in multidomain proteins--studies of isolated domains are not enough.
Randles LG, Dawes GJ, Wensley BG, Steward A, Nickson AA, Clarke J
FEBS J, 2013-02, 4, 1018-1027. DOI: 10.1111/febs.12094


Slow, reversible, coupled folding and binding of the spectrin tetramerization domain.
Shammas SL, Rogers JM, Hill SA, Clarke J
Biophys J, 2012, 10, 2203-2214. DOI: 10.1016/j.bpj.2012.10.012


Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
Alessandro Borgia, Beth G Wensley, Andrea Soranno, Daniel Nettels, Madeleine B Borgia, Armin Hoffmann, Shawn H Pfeil, Everett A Lipman, Jane Clarke, Benjamin Schuler
Nature_Communications DOI: 10.1038/ncomms2204


Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains.
Wensley BG, Kwa LG, Shammas SL, Rogers JM, Browning S, Yang Z, Clarke J
Proc Natl Acad Sci U S A, 2012, 44, 17795-17799. DOI: 10.1073/pnas.1201793109


Protein folding: Adding a nucleus to guide helix docking reduces landscape roughness
Wensley BG, Kwa LG, Shammas SL, Rogers JM, Clarke J
Journal of Molecular Biology, 2012, 3, 273-283.


Two immunoglobulin tandem proteins with a linking β-strand reveal unexpected differences in cooperativity and folding pathways
Steward A, Chen Q, Chapman RI, Borgia MB, Rogers JM, Wojtala A, Wilmanns M, Clarke J
Journal of Molecular Biology, 2012, 1, 137-147.


Staphylococcal biofilm-forming protein has a contiguous rod-like structure
Gruszka DT, Wojdyla JA, Bingham RJ, Turkenburg JP, Manfield IW, Steward A, Leech AP, Geoghegan JA, Foster TJ, Clarke J, Potts JR
Proceedings of the National Academy of Sciences of the United States of America, 2012, 17, E1011-E1018.


Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
Borgia A, Wensley BG, Soranno A, Nettels D, Borgia MB, Hoffmann A, Pfeil SH, Lipman EA, Clarke J, Schuler B
Nature Communications, 2012, -.


Learning from Nature to design new biomolecules
Clarke J, Schief W
Current Opinion in Structural Biology, 2012, 4, 395-396.