the goodman group
university of cambridge  


   tamiflu
tamiflu

Alternate names

oseltamivir


Literature

Tamiflu is a treatment for flu, which inhibits neuraminidase.

Review:
The synthetic development of the anti-influenza neuraminidase inhibitor oseltamivir phosphate (Tamiflu): A challenge for synthesis and process research
S. Abrecht, P. Harrington, H. Iding, M. Karpf, R. Trussardi, B. Wirz and U. Zutter. Chimia, 2004, 58, 621-629.

Synthesis:
A Short Enantioselective Pathway for the Synthesis of the Anti-Influenza Neuramidase Inhibitor Oseltamivir from 1,3-Butadiene and Acrylic Acid
Y.Y. Yeung, S. Hong and E. J. Corey. J. Am. Chem. Soc. 2006, 128, 6310-6311.


SMILES

Canonical SMILES

InChI

MInChI v0.9
MInChIxe1 C16H28N2O4 c1xh5xh12xl6 xh2xr22xh14x h9xh11xl16xl 20xr21xh7xh3 xr8xh13xl17x r15xl14xr18x h10xl4xr19xs h9xc12xh15Hx c5xh8xc17H2x c1xh4H3xcxlH xc18xc19xrxs t13xhxc14xpx c15xpxsm0xss 1


Structure files

MOL file ; PDB file

Conformation
1000 step GACK search using MM2* forcefield


Updated: 9 June 2006



© Goodman Group, 2005-2017; privacy; last updated September 21, 2017

department of chemistry University of Cambridge