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   Strecker Reaction
Mechanism of BINOL-Phosphoric Acid-Catalyzed Strecker Reaction of Benzyl Imines
L. Simon and J. M. Goodman J. Am. Chem. Soc. 2009. 131, asap
DOI: 10.1021/ja808715j

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Building on the work reported in ja800793t we examined Strecker reactions. A minor modification to the transition state picture (below) allows us to account for the experimental data, and to make a prediction about a reaction the product of which has an unknown absolute configuration.


Related work is described in ja800793t and in jo8007463


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department of chemistry University of Cambridge