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Strecker Reaction
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Mechanism of BINOL-Phosphoric Acid-Catalyzed Strecker Reaction of Benzyl Imines
L. Simon and J. M. Goodman J. Am. Chem. Soc. 2009. 131, asap
DOI: 10.1021/ja808715j
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Building on the work reported in ja800793t we examined
Strecker reactions. A minor modification to the transition state picture (below) allows us to account for the experimental
data, and to make a prediction about a reaction the product of which has an unknown absolute configuration.
Related work is described in ja800793t and in jo8007463
#sketchBINOL
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